This Project Grant award of $162,820 from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research federal grant program (CFDA 93.837), supports research to develop a community-clinical linkage model to facilitate referral of people living with HIV (PLWH) and comorbid hypertension to primary healthcare centers in Akwa Ibom, Nigeria. The research aims are to: 1) identify barriers and facilitators to this model, 2) co-develop a culturally-tailored,...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), a division of the National Institutes of Health (NIH), is focused on understanding the mechanisms underlying HIV-associated hypertension and cardiovascular disease. The $641,960 award, granted to the Augusta University Research Institute, Inc. (doing business as Georgia Health Sciences), will fund research to investigate how HIV-derived proteins, specifically the Tat protein, contribute to the development of...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Federal Grant Program for Cardiovascular Diseases Research (CFDA 93.837), provides $123,104 to Emory University to conduct research on factors contributing to cardiovascular disease (CVD) comorbidities in persons living with HIV (PWH). The key objectives are to: 1) assess relationships between the metabolome, lipidome, HIV reservoir, and subclinical CVD, analyzing differences by sex; and 2) determine...
This Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) to the Augusta University Research Institute, Inc. (doing business as Georgia Health Sciences) will support $2,282,280 in research over the period from August 2024 to May 2028. The grant will fund investigations into the role of HIV-derived proteins, CD4+ T cells, and the protein podocan-like protein 1 (PODNL1) in the development of pulmonary vascular disease (PVD) among...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under CFDA Program 93.837 - Cardiovascular Diseases Research provides $249,000.00 to The University of Iowa to conduct research on "Mechanisms that Enhance and Suppress HIV-1 Resistance in Gene Edited Primary Human Cells." The project aims to develop a multi-factor gene editing strategy to modify hematopoietic stem and progenitor cells to enhance resistance against HIV-1 infection. The research will...
This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) at the National Institutes of Health will support research to determine the pathophysiological mechanism and potential therapeutic approaches for alleviating HIV-associated chronic obstructive pulmonary disease (COPD). The total award amount is $1,405,336 over the project period from September 1, 2024 to May 31, 2028. The primary focus is on investigating how HIV and...
This $221,635 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support a community-engaged modeling and implementation science project to develop re-linkage interventions for Black sexual minority men with HIV. The project aims to use agent-based modeling, qualitative data, and implementation science methods to characterize barriers to HIV care engagement and identify strategies to improve re-linkage,...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $1,321,108 Project Grant under CFDA 93.837 (Cardiovascular Diseases Research) to New York University School of Medicine to conduct transdisciplinary implementation research on a strategy called PT4A. PT4A integrates peer-based medication delivery, peer coaching, and health information technology to improve medication adherence and reduce blood pressure among patients with uncontrolled hypertension in Western Kenya. The study aims to...
This federal Project Grant award with ID R61HL172269, totaling $724,064.00, was provided by the National Heart Lung and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The award will fund the development and evaluation of a multi-level, integrated intervention called "HTN-Urban" to improve hypertension control among adults living in urban Vietnam. Key components of the intervention include a storytelling program, home blood pressure...
This $565,250 federal Project Grant award was provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The grant supports a 5-year longitudinal study led by Duke University to characterize the effects of host-microbiome interactions on pulmonary function in a cohort of 500 adults with and without HIV in Botswana. The study will utilize advanced multi-omics techniques, including shotgun metagenomic sequencing, host...