Understanding dynamic correlates of children's telomere length: the interplay between cumulative risk exposure and relational processes
Ended Project Grant Awarded Last action
- Award ID
- R03HD112639
- Recipient
-
University Of Illinois UEI Y8CWNJRCNN91
- Awarding agency
-
National Institute of Child Health and Human Development
National Institutes of Health, Department of Health and Human Services
- Obligated
- $286,940
Award facts
- Assistance listing
- 93.865 Child Health and Human Development Extramural Research
- Completion date
- Originally
- Place of performance
- Illinois, USA
Award details come from USAspending.gov.
Description
- Abstract
- Reductions in telomere length (TL), a biomarker of cellular stress, are linked with later atypical human development, including elevated risk for psychopathology, chronic disease, and mortality. Understanding factors that either positively or negatively impact children's TL is needed to enhance children's long-term health and well-being. Currently, stress-inducing adverse experiences (risk exposures), such as household economic strain, exposure to violence, and neighborhood disadvantage, have both an independent and a dose- dependent effect on TL, with the occurrence of each additional adverse experience accelerating TL shortening. Prior work in this area is limited, however, in that IT has conceptualized risk exposures as static rather than dynamic and has failed to investigate protective factors that mitigate the effect of cumulative risk exposures on children's outcomes. The proposed project aims to (1) examine how fluctuations in cumulative risk exposure are prospectively associated with children's telomere length and (2) examine how parents' supportiveness towards each other serves as a moderator between cumulative risk exposure and children's telomere length. To achieve these aims, the research team will conduct a dyadic, longitudinal analysis of data from the fragile families and child wellbeing study (ffcwb). Findings from this project will contribute to a broader understanding of factors that positively or negatively impact children's TL and elucidate sensitive periods in which cumulative exposure to adverse experiences may be most harmful for children.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $0 | |
| Amendment | -$0 | |
| Amendment | -$0 | |
| Amendment | $103,758 | |
| Amendment | -$110,111 | |
| Amendment | $103,758 | |
| Amendment | -$110,111 | |
| Amendment | -$110,111 | |
| Amendment | $103,758 | |
| Amendment | $0 | |
| Amendment | $153,000 | |
| Original award | $153,000 |
Show all 12
Subawards
| Subrecipient | Amount | Awarded |
|---|---|---|
| University Of Tennessee | $39,776 |
Quick answers
Who received award R03HD112639?
R03HD112639 was awarded to University Of Illinois by National Institute of Child Health and Human Development (National Institutes of Health) on August 7, 2023.
How much is award R03HD112639 worth?
$286,940 has been obligated on R03HD112639.
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