Project Grant R03DK144848
- This $809,427 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research on the impact of polymicrobial interactions and within-host adaptation on the pathogenesis of catheter-associated urinary tract infections (CAUTI). The award recipient, The Research Foundation For The State University Of New York (RF SUNY) doing business as Sponsored...
- This Project Grant award, totaling $377,648, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant supports research on the role of Proteus mirabilis RTX proteins in polymicrobial biofilm formation and the pathogenesis of catheter-associated urinary tract infections (CAUTIs). The research aims to examine the expression of P. mirabilis RTX proteins during polymicrobial biofilm...
- This $117,000 Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), to the Research Institute at Nationwide Children's Hospital. The project aims to define the mechanisms by which the transcription factor STAT3 contributes to antimicrobial host defense in the human urothelium (bladder lining) against urinary tract infections (UTIs). Key...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $234,750 to the University of Notre Dame to conduct research on polymicrobial interactions during catheter-associated urinary tract infections (CAUTI). The key objectives are to: Investigate the antagonistic effects of Escherichia coli (E. coli) against Candida albicans (C. albicans), specifically examining the...
- This federal Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $3,005,541.00 to Baylor College of Medicine to conduct research on the mechanisms driving age-dependent and sex-dependent changes in bladder immunity that contribute to recurrent urinary tract infections (UTIs) and other lower urinary tract disorders in older women. The...
- This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $653,123 to The University of Texas Southwestern Medical Center (UT Southwestern) to conduct a multi-center randomized trial comparing daily nitrofurantoin versus bladder fulguration plus daily nitrofurantoin for the long-term management of cystitis in women with recurrent urinary tract...
- This Project Grant award was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The $188,916 award supports research by Brigham & Women's Hospital Inc. to investigate how the bacterium Staphylococcus aureus, a leading infectious cause of death globally, is able to evade the immune system and persist during bloodstream infections. The research aims to determine how noncytotoxic (non-toxic)...
- This Project Grant award of $115,123 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to reveal strategies for eradicating antibiotic-tolerant Staphylococcus aureus persister cells. The research aims to identify the host cells harboring intracellular S. aureus reservoirs and characterize the host and bacterial transcriptomes using single-cell approaches. Additionally, the project...
- This $3,400,004 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to investigate the role of waterborne Escherichia coli transmission as a cause of community-acquired urinary tract infections (UTIs). The key objectives are to: (1) model the drivers and dynamics of E. coli contamination in water systems, (2) identify socio-behavioral, epidemiological, genomic, and...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $176,201 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of California, Irvine. The grant, with an award date of July 15, 2025 and an ultimate completion date of March 31, 2030, will fund research to investigate the molecular changes in aging female urethral striated muscle and develop potential treatments for urethral dysfunction,...
This Project Grant award of $226,253 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to elucidate the adaptations of Staphylococcus aureus that enable its persistence within the bladders of long-term catheterized individuals. The research will be conducted by the University of Texas Health Science Center at Houston (UTHealth) from September 1, 2025 through August 31, 2027. The project focuses on improving understanding of the factors contributing to asymptomatic bacteriuria and catheter-associated urinary tract infections (CAUTIs) caused by S. aureus, which are common complications of long-term urinary catheterization. The research findings are expected to inform strategies for prevention and management of these healthcare-associated infections.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $226.3k | 8/22/25 |