Project Grant R03DK144287
- This $224,088 federal Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award aims to investigate the physiological regulation of energy intake at meals following weight loss. The research will leverage data from two ongoing NIDDK-funded studies - the ARROW study, which examines predictors of long-term weight loss maintenance, and the...
- This Project Grant award of $118,122 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports a study investigating the role of gastrointestinal interoception (the processing of internal bodily sensations) in the maintenance of disordered eating behaviors. The study aims to 1) determine whether visceral sensitivity leads to the daily maintenance of restrictive and compensatory eating behaviors, and 2) identify the mechanisms...
- This Project Grant award of $151,040, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research examining sex-specific effects and the role of ovarian hormones in striatal-mediated food-seeking behaviors. The project, conducted by the Regents of the University of Michigan, aims to provide insight into how excitatory neurotransmission is regulated in...
- This Project Grant award, totaling $123,908, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The funding supports research at Baylor College of Medicine to investigate the role of the ANO4 calcium-activated chloride channel in the area postrema (AP) region of the brain, and its potential involvement in the orexigenic (appetite-stimulating) effects of the...
- This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $120,792 to the University of Alabama at Birmingham to conduct research assessing the mechanistic relationships between central amygdala neuron activity and glucagon-like peptide-1 receptor agonism. The project aims to pursue a functional analysis of GLP-1 receptors in the control of...
- This Project Grant award of $666,229 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) supports research on the role of the neuropeptide neurotensin (NTS) in the lateral nucleus accumbens (NACLat) to ventral tegmental area (VTA) pathway and its impact on hedonic feeding behavior. The project aims to study how NTS signaling in this neural pathway modulates reward-related feeding in mice, both on...
- This federal Project Grant award in the amount of $427,000 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to President & Trustees of Williams College. The award is funding a research project to study the role of the parasubthalamic nucleus (PSTN) in regulating feeding behavior and appetite suppression. The key objectives are to determine the afferent...
- This federal Project Grant award, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to investigate how the sympathetic nervous system regulates ghrelin secretion. The $637,124 grant, awarded to the University of Texas Southwestern Medical Center, will fund a 5-year research project to determine how fasting and exercise impact the sympathetic...
- The $441,000 Project Grant awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will support research by the CAL Poly Pomona Foundation Inc. to identify a dopamine circuit in the brain that mediates day eating and diet-induced obesity in mice. The 3-year project seeks to genetically and anatomically define a subpopulation of dopaminergic neurons in the ventral tegmental...
- This Project Grant award of $249,000.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) to New York University aims to improve understanding of how hunger and satiety neurons regulate the activity of downstream neurons in the hypothalamus. Specifically, the research will use novel molecular and optical tools to measure and manipulate cyclic AMP (cAMP) signaling in paraventricular hypothalamic neurons that express melanocortin-4 receptors (PVHMC4R), which...
This $201,000 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research) supports research to examine the biological mechanisms underlying problematic avoidant/restrictive eating behaviors in adults with functional dyspepsia (FD). The study aims to identify whether the hormones oxytocin and glucagon-like peptide 1 (GLP-1) are associated with these eating behaviors in FD patients. The research will analyze biospecimens collected from two parent studies: an observational cross-sectional study and a pilot feasibility randomized controlled trial of a behavioral treatment for FD patients. The project will expand on the parent K23-supported studies by evaluating these additional candidate anorexigenic hormones as potential mechanisms underlying the problematic eating behaviors observed in a significant portion of adults with FD.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $201.0k | 8/1/25 |