This $509,969 federal Project Grant was awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research to elucidate the neural mechanisms regulating feeding behavior and body weight control, with a focus on the role of the anoctamin 4 (ANO4) ion channel in the area postrema of the hindbrain. Key objectives include: 1) determining the physiological...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is focused on investigating the role of glucagon-like peptide-1 (GLP-1) and its receptor agonists in regulating neuropeptide Y/agouti-related peptide (NPY/AGRP) neuron activity and metabolism. The $410,000 award, with a performance period from August 2024 to August 2025, will support research...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $120,792 to the University of Alabama at Birmingham (UAB) to conduct research on the role of glucagon-like peptide-1 receptor (GLP-1R) agonism in the central amygdala and its impact on appetite and food intake regulation. The award period runs from Dec 1, 2024 to Apr 29, 2025. The...
This Project Grant award for $502,233 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The funding supports research at the University of Michigan to investigate neuron populations in the nucleus of the solitary tract (NTS) that mediate both aversive and non-aversive suppression of food intake. The researchers aim to use molecular genetic techniques to...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is funding research at Williams College to study the role of the parasubthalamic nucleus (PSTN) in regulating feeding behavior. The $427,000 award spans from April 2025 to March 2028 and aims to investigate the afferent connectivity, activity patterns, and necessity of PSTN subpopulations in...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $640,762 to the Scripps Research Institute to investigate the role of intestine-secreted proteins in regulating white adipose tissue (WAT) metabolism and obesity development. The project aims to map the interorgan communication network between the intestine and WAT depots, define the...
This federal Project Grant award for $390,000 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant will support research to investigate the role of the inward rectifier potassium channel KIR7.1 in regulating energy homeostasis and its potential as a therapeutic target for obesity. The research project, conducted by the Regents of the University of...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) totaling $194,616 will support research to uncover the role of the G-protein coupled receptor GPR39 in kidney physiology. The key objectives are to: Examine three potential mechanisms by which activation of GPR39 influences the trafficking of the water channel protein AQP2 in vitro. This includes...
This federal Project Grant award of $176,500.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research investigating the interrelated roles of hypothalamic microglia activation and perineuronal net loss in the pathogenesis of diet-induced obesity. The key objectives are to quantify how microglia regulate arcuate nucleus perineuronal net turnover, determine...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $148,568 to support research investigating the physiological regulation of energy intake during meals following weight loss. The award will fund a study to analyze energy balance and gut hormone data from the ARROW Study (R01DK114272) and the TIME2EAT Study (R01DK132372) to better...