Project Grant R03DE034768
- The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded a $1,207,004 cooperative agreement to the University of North Carolina at Chapel Hill (UNC-CH) to conduct a clinical trial evaluating the safety and analgesic (pain-relieving) efficacy of a marine oil supplement in adults with chronic temporomandibular disorder (TMD) pain. The study will investigate the inflammation-resolving,...
- This Project Grant award, with an ID of R01DE032676, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279). The $2,372,115 award, spanning from July 2024 to June 2027, supports research to identify and validate the lysophosphatidic acid (LPA)/LPA receptor (LPAR) signaling pathway as a novel target for the treatment of temporomandibular disorder (TMD) pain. The primary research objectives are to: 1)...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $312,000 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to the Regents of the University of Michigan Office of Research and Sponsored Projects to establish the Michigan Collaborative Hub for TMD Patient-Centric Research (MICH T PCR). The goal of the award is to transform the treatment of temporomandibular disorders (TMDs) through the translation of clinically-relevant innovations. The...
- The University of North Carolina at Chapel Hill was awarded a $130,122 Project Grant by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research (CFDA 93.121) program. The grant supports research investigating the roles of the chromatin-modifying enzymes KMT2C and KMT2D in chondrocyte differentiation and endochondral ossification, which are critical processes for craniofacial and skeletal development. The project aims to utilize genomic...
- This federal Project Grant award in the amount of $299,782.00 was provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121). The funding supports the development and validation of an MRI-compatible jaw metabolic stressor task to determine the jaw muscle metabolic stress and brain functional characteristics related to jaw pain perception during function. This research aims to create new models for studying...
- This Project Grant award of $18,438.00, provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), supports research on cellular heterogeneity and niche regulation in temporomandibular joint (TMJ) osteoarthritis. The research aims to define unique cell subpopulations in the TMJ and examine how impaired organization of the fibrous superficial layers of the mandibular condyle alters TMJ progenitor cell...
- This Project Grant award of $419,379 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), is supporting research to investigate the molecular mechanisms by which Notch signaling regulates temporomandibular joint (TMJ) osteoarthritis. The goal is to develop new therapeutic approaches to prevent TMJ degeneration and facilitate regeneration. The award, with a performance period from August 2025...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $655,455 Project Grant to The Trustees of Columbia University in the City of New York under the Oral Diseases and Disorders Research (CFDA 93.121) program. The purpose of this 2-year award, effective from Sep 11, 2025 to Sep 10, 2027, is to investigate candidate temporomandibular joint (TMJ) cartilage progenitor cells and their regulatory niche critical for TMJ development, homeostasis, and regeneration. The research...
- This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), provides $105,450.00 to Midwestern University to develop and test a Virtual Patient-Based Learning (VPBL) methodology for improving dental education in Temporomandibular Disorders (TMD). The project aims to address gaps in TMD education by incorporating real patient data into interactive clinical scenarios and...
- The University of Pittsburgh was awarded a $400,000 Cooperative Agreement under the Trans-NIH Research Support program (CFDA 93.310) by the National Institutes of Health (NIH) with a start date of September 9, 2025 and an ultimate completion date of June 30, 2030. The award will fund the Collaborative for Research to Advance TMD Evidence (CREATE) project, which aims to address critical gaps in the understanding of temporomandibular disorders (TMDs) through a bidirectional approach integrating...
The University of North Carolina at Chapel Hill received a $310,295 Project Grant from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research (CFDA 93.121) program. The grant, awarded on September 11, 2025, with a completion date of September 10, 2027, supports research to identify subgroups of adolescents with chronic temporomandibular disorder (TMD) pain in order to guide personalized treatment approaches. The project aims to characterize the physiological processes and psychosocial factors associated with chronic TMD pain in adolescents, with the goal of developing a biobehavioral intervention called Physical Self-Regulation that can be tailored to individual patient profiles. The research findings are expected to advance scientific understanding and treatment strategies for this common chronic pain condition affecting up to 30% of adolescents.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $310.3k | 9/11/25 |