Project Grant R03DE033064
Award Date 8/15/23
Completion Date 8/14/25
Dollars Obligated $317K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Hatboro, PA 19040, USA
Similar Awards
- The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded a $716,123 Project Grant to the H. Lee Moffitt Cancer Center and Research Institute Hospital, Inc. in Florida. The grant, awarded on September 8, 2025, aims to establish a clinical cohort and develop novel analytical methodologies to validate, discover, and optimize non-invasive liquid biopsy tests for prognosis prediction in head and...
- The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded a $219,660 Project Grant to the Regents of the University of Michigan to conduct research on "Intercepting the Evolution of Pro-Tumoral Myeloid Cells During the Initiation of Oral Cancer". This project aims to investigate how myeloid cells in precancerous lesions develop suppressive phenotypes that inhibit anti-tumor immune...
- This Project Grant award of $315,000.00 was provided by the National Institute of Dental and Craniofacial Research (NIDCR), which administers the Oral Diseases and Disorders Research federal grant program (CFDA 93.121). The goal of this 2-year project is to study the role of the TRPC1 protein as a potential therapeutic target for treating oral squamous cell carcinoma (OSCC), a common and deadly type of head and neck cancer. The research will focus on understanding how TRPC1 mediates calcium...
- This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), provides $170,208 to The Washington University in Missouri to conduct research on targeting polyamine (PA) metabolism to increase immune responses to head and neck squamous cell carcinoma (HNSC). The proposed four-year research plan aims to define the mechanisms through which PAs modulate anti-tumor immunity, with...
- This federal Project Grant award of $3,742,682 was provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) to the Dana-Farber Cancer Institute, Inc. (DFCI) in Massachusetts. The grant supports research to dissect the role of the chemokine CCL5 in shaping antigen-specific T cell responses against head and neck cancers. Key objectives include: Investigating how CCL5 chemokine networks impact the development...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $390,000 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to The Medical College of Wisconsin, Inc. The grant funds a 5-year research project to leverage single-cell co-culture and gene expression profiling to identify tumor antigen-specific T cells in oral squamous cell carcinoma (OSCC). The project aims to develop innovative methods to isolate and characterize tumor-infiltrating...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $129,289 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to The Leland Stanford Junior University. The grant funds research to develop lysosome-targeting chimeras (LYTACs) that can degrade immune checkpoint proteins and enhance immunoradiotherapy for head and neck cancer. The project aims to evaluate the impact of LYTACs on immune cell modulation and their therapeutic potential in...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $421,625 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to the Texas A&M Engineering Experiment Station (Tees) to develop advanced tumor microenvironment chips (TME-chips) that incorporate functional blood and lymphatic capillary networks. The objective is to create innovative in-vitro systems that can accurately model oral squamous cell carcinoma (OSCC) tumor microenvironments,...
- This federal Project Grant award of $249,000.00, provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), supports research to develop a novel patient-derived tumor organoid (tumoroid) platform for precision treatment of head and neck squamous cell carcinomas (HNSCCS). The key products and services to be delivered include: Establishing a high-throughput automated HNSCC tumoroid platform to capture tumor...
- The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded a $616,000 Project Grant to the Rowan University School of Osteopathic Medicine. This grant, with a performance period from Aug 1, 2025 to Jul 31, 2029, will support research investigating the use of the Hedgehog signaling pathway inhibitor drug sonidegib as a potential therapeutic strategy for oral squamous cell carcinoma (OSCC). The key...