Project Grant R03AI199321
- Federal Grant Award Summary The University of Southern Mississippi received a $235,822 Project Grant award dated July 23, 2025, from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award supports research investigating the role of tick phospholipase A2 (PLA2) in alpha-gal syndrome (AGS), a meat allergy triggered by lone star tick bites. The research addresses a significant public health threat, as...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $417,845 to the University of Nebraska Medical Center under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a two-year project period from August 1, 2025, through July 31, 2027. The award supports the development and adaptation of an innovative in vitro organotypic human skin model designed to enable tick feeding and study the transmission and colonization of Borrelia...
- Federal Grant Award Summary Stony Brook University, operating under The Research Foundation For The State University of New York, received a $436,605 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award, dated February 4, 2026, with a completion date of January 31, 2028, funds research investigating the capacity of Haemophysalis longicornis (longhorned tick) to acquire and transmit...
- Federal Grant Award Summary Baylor College of Medicine received a $797,087 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 18, 2026, with completion scheduled for January 31, 2031. The research focuses on defining the molecular mechanisms driving transovarial transmission (TOT)—the vertical transmission of pathogens from infected ticks to their offspring—using...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The University of Southern Mississippi $750,000 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on September 20, 2025, with a completion date of August 31, 2029. This Project Grant supports investigator-initiated research aimed at elucidating the role of extracellular polyphosphate in Mycobacterium tuberculosis (MTB) antibiotic tolerance, with particular focus on how the...
- Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $1,041,346 to the University of Maryland, College Park under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct fundamental research on cross-species signaling mechanisms in tick immunity and development. Awarded on July 17, 2025, with a completion date of June 30, 2030, this project grant will investigate how Ixodes scapularis ticks sense and respond to mammalian-derived...
- Federal Grant Award Summary Georgia Southern University Research & Service Foundation Inc. received a $710,000 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective June 1, 2025, through May 31, 2028. The project delivers comprehensive morphological and molecular identification tools for Hyalomma tick species that vector Crimean-Congo Hemorrhagic Fever (CCHF) virus, which...
- Federal Grant Award Summary Baylor College of Medicine received a $200,625 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded May 5, 2026, with completion targeted for April 30, 2028. The research project, "Unraveling Vector Ecology and Genomic Drivers of Vertical Transmission: Defining Relapsing Fever Borrelia Persistence in Populations of the Under-Studied Argasid Tick,...
- Federal Project Grant Award Summary Washington State University received a $229,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded May 22, 2026, with a completion date of April 30, 2028. The research focuses on dissecting the antimicrobial network orchestrated by the noncanonical Immune Deficiency (IMD) pathway in ticks, specifically investigating how the Ixodes tick immune...
- Federal Grant Award Summary Texas A&M Agrilife Research received a $423,106 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, through July 31, 2027. The award supports research to characterize the role of tick metalloprotease inhibitors in the transmission of Borrelia burgdorferi, the causative agent of Lyme disease, by blacklegged nymphal ticks. The research...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded The University of Southern Mississippi $150,000 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a two-year project period (June 1, 2026 – May 31, 2028). This Project Grant funds research focused on manipulating the piWI-interacting RNA (piRNA) pathway to generate sterile ticks as a novel approach to sterile insect technology (SIT). The research will establish a mechanistic framework for piRNA-based SIT by disrupting the tick piRNA pathway, which is expected to induce sterility through transposable element derepression and impaired germline genome integrity. The primary deliverable is the development of a comprehensive piRNA knockdown signature characterized by transposable element derepression and sterility outcomes. The research outcomes will provide a rational scientific foundation for developing piRNA-based SIT platforms targeting tick vectors of public health significance and will be extensible to other tick species. This work addresses a critical gap in vector control strategies by leveraging fundamental knowledge of genome surveillance mechanisms to reduce tick population fitness and potential pathogen transmission capability.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $150.0k | 6/1/26 |