Project Grant R03AI196747
- Federal Grant Award Summary The University of Chicago received a $807,799 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 15, 2025, through June 30, 2030. This research initiative focuses on identifying and characterizing B cell-dependent regulatory T cells (BCD Tregs)—specialized immune cells that directly interact with B cells to control self-reactive B cell...
- Federal Grant Award Summary The University of Chicago received a $3.02 million Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 8, 2025, with completion targeted for June 30, 2029. This award supports investigator-initiated biomedical research focused on elucidating the role of BRWD1-mediated cohesin conversion in B cell biology and function. The research examines how...
- Federal Grant Award Summary The University of Chicago received a $451,000 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 5, 2026, through January 31, 2028. This research initiative focuses on identifying novel cellular targets and mechanisms to enhance targeted RNA degradation (TRD) technologies for antiviral drug development. The project addresses a critical...
- Federal Grant Award Summary The University of Chicago received a $766,265 Project Grant award dated July 23, 2025, from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on transplantation tolerance mechanisms through June 30, 2030. The grant funds investigative research into the role of regulatory T cells (Tregs) in acquiring and maintaining conventional T cell (Tconv) anergy in...
- Federal Project Grant Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $451,000 Project Grant to the University of Chicago effective June 17, 2025, through May 31, 2027, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This award funds investigator-initiated biomedical research focused on understanding how retroviruses, specifically Mouse Mammary Tumor Virus (MMTV), manipulate antibody responses and evade host protective immunity. The...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Chicago a Project Grant totaling $218,164 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period August 25, 2025, through March 31, 2029. The award funds investigator-initiated biomedical research aimed at defining the immunological mechanisms driving the differentiation and functional potential of memory-phenotype CD8+ T cells (CD8-MP...
- Federal Project Grant Award Summary The University of Illinois received a $736,822 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 1, 2026 through January 31, 2031. This award funds fundamental research investigating the mechanisms by which bacterial lipases enable pathogenic adaptation to the host lipid environment, with specific focus on Staphylococcus...
- Federal Grant Award Summary Loyola University of Chicago's Health Sciences Campus received a $423,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 2, 2026, through January 31, 2028. The award funds biomedical research aimed at elucidating the mechanisms by which inflammatory bowel disease (IBD)—including Crohn's disease and ulcerative colitis—induces central...
- Federal Grant Award Summary Northwestern University received a $200,000 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective September 4, 2025, with a completion date of August 31, 2027. The award supports biomedical research focused on identifying and validating microRNAs (miRNAs) that regulate neutrophil transendothelial migration (TEM) in gut inflammation. The research...
- Federal Grant Award Summary The University of Illinois received a $582,350 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 8, 2025, with completion targeted for June 30, 2030. The grant funds investigator-initiated research to identify microbiota-mediated colonization resistance mechanisms against Acinetobacter baumannii, a multidrug-resistant pathogen that poses...
The University of Chicago received a $164,000 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded April 2, 2026, with a completion date of March 31, 2027. The award funds basic biomedical research investigating the intrinsic role of the SLC4A2 gene in the development of liver inflammation and autoimmune cholangitis using conditional knockout mouse models. The research aims to dissect the mechanisms by which SLC4A2 deficiency contributes to primary biliary cholangitis (PBC), a chronic autoimmune cholestatic liver disease, by characterizing immune cell composition in liver and lymphoid organs and studying alterations in T cells and liver cells in the absence of SLC4A2 function. The research products delivered through this award will include characterization data on immune cell populations in tissue-specific SLC4A2 conditional knockout mice, mechanistic findings regarding the role of SLC4A2 in immune tolerance and autoimmune cholangitis development, and scientific knowledge intended to advance understanding of PBC etiopathogenesis and inform future therapeutic development approaches for affected patients. The work is conducted at the University of Chicago in Chicago, Illinois, and contributes to NIAID's broader mission of supporting investigator-initiated research addressing infectious diseases, allergic conditions, and immunologic disorders.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $164.0k | 4/2/26 |