Project Grant R03AI178099
- This Project Grant award of $226,980 was provided by the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research (CFDA 93.855) federal grant program. The funding will support research at Thomas Jefferson University to investigate the role of the GPR15-C10ORF99 pathway in T cell homing during eosinophilic esophagitis (EoE). EoE is a chronic inflammatory disease characterized by eosinophilic infiltration of the esophagus, which can lead...
- The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855), awarded a $3,375,359 Project Grant to The Children's Hospital of Philadelphia (CHOP) to conduct research on the impact of cytokine signaling on epithelial reprogramming and barrier dysfunction in eosinophilic esophagitis (EOE). The project aims to examine the specific roles of STAT3 and STAT1 in regulating STAT6-driven epithelial barrier...
- This federal Project Grant award of $183,600.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant will support a 5-year research and career development plan for the principal investigator, Dr. Amiko Uchida, to investigate how dietary changes impact the gut microbiome composition and function in patients with eosinophilic esophagitis (EoE), a chronic...
- This federal Project Grant award of $1,222,594.00, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research investigating the role of glutathione peroxidase 3 (GPX3) in regulating esophageal epithelial remodeling, subepithelial fibrosis, and eosinophil recruitment in eosinophilic esophagitis (EoE). The research, led by the primary awardee Vanderbilt...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $743,752 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Utah. The grant will support research to define how chronic antigen stimulation contributes to epigenetic programming that drives dysfunction in virus-specific CD4+ T cells during chronic viral infection. The project aims to use highly innovative in vivo models and whole genome DNA methylation sequencing...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $248,088 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Johns Hopkins University on January 12, 2025. The research aims to examine the role of immunoglobulin E (IgE) and the sugar-binding protein galectin-3 in the activation of basophils, which are immune cells involved in allergic reactions. Specifically, the project will compare galectin-3-dependent basophil activation...
- This $433,423 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will support research to characterize the epithelial ER-phagy-IFN axis in influenza infection. The research aims to determine how specific ER-phagy receptors in lung epithelial cells regulate influenza viral burden in an IFN-dependent manner, providing insights into controlling viral burden and mitigating virus-induced...
- This federal Project Grant award of $586,250 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will support research at the University of Massachusetts Medical School (UMass Medical) to investigate the generation and regulation of TFH13 cells that drive pathogenic IgE in allergic conditions. The overarching goal is to elucidate the pathways leading to TFH13 cell differentiation, which play a critical...
- The federal Project Grant award titled "ADIPOCYTE-EOSINOPHIL COMMUNICATION AND ITS ROLE IN REGULATION OF AIRWAY FUNCTION" is being provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The $730,392 grant, awarded on June 17, 2025, supports research conducted by the University of Colorado-Denver to investigate the role of adipose tissue and eosinophils in regulating airway function and...
- This $486,109 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855), supports research to define and investigate methods for amplifying type 2 immune responses of eosinophils in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). The research aims to understand how eosinophils may contribute to the repair and resolution of lung injury through increased type...
This $153,799 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to characterize the molecular pathways responsible for the initiation and persistence of eosinophilic esophagitis (EoE), a highly inflammatory condition of the esophagus. The University of Utah will conduct RNA sequencing of esophageal tissues during food elimination and reintroduction diets to differentiate the specific epithelial and immune pathways involved in the acute and chronic stages of EoE. This research aims to identify early biomarkers of EoE development in order to enable earlier disease detection and personalized therapeutic interventions to reduce the substantial healthcare burden associated with this condition. The project will be conducted from August 2025 through July 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $153.8k | 8/12/25 |