The University of Massachusetts Medical School (UMMS) was awarded a $586,250 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant, which runs from November 12, 2024 to October 31, 2029, supports research to elucidate the pathways that lead to the differentiation of TFH13 cells, a novel T follicular helper cell subset that drives the production of high-affinity, pathogenic IgE antibodies in allergic diseases. The overarching goal is to understand the distinct immunological requirements for the differentiation of TFH2 and TFH13 cells, with the potential to identify targets for curtailing allergic disease.
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