Project Grant R03AG093555

Award Date 5/1/25
Completion Date 4/30/27
Dollars Obligated $301K
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
Tucson, AZ 85721, USA
Similar Awards
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $307,000.00 to the University of Arizona to conduct a study on the effects of early Alzheimer's disease pathogenesis on episodic memory accuracy and precision. The study aims to identify memory processes that are sensitive to the asymptomatic, preclinical stage of Alzheimer's disease by combining a continuous report item-location associative memory task with advanced behavioral and...
The National Institute on Aging (NIA) awarded a $5,262,301 project grant under the Aging Research Federal Grant Program (CFDA 93.866) to Trustees of Boston University (Boston University Medical Campus) for the "Improving Causal Inference in Alzheimer's Disease Prevention Research on Modifiable Risk Factors: The Triangulation of Innovative Methods to END AD (TIME-AD) Project". The 5-year award, effective September 15, 2024, will support a comprehensive research program focused on...
The National Institute on Aging (NIA), part of the Department of Health and Human Services National Institutes of Health, awarded a $3.37 million Project Grant to The University of Texas at Arlington to develop an individualized deep connectome framework for Alzheimer's disease and related dementias (ADRD) analysis. The three-year grant, awarded on August 18, 2022 under the NIA's Aging Research program (CFDA 93.866), will support research to discover and identify individualized...
This Project Grant from the National Institutes of Health's National Institute on Aging, under the Aging Research program (CFDA 93.866), provides $2,251,070 to the University of California Irvine through July 2025. The grant supports research to develop new statistical methodologies for analyzing Alzheimer's disease data from longitudinal cohort studies. Key deliverables include methods for assessing prediction precision for recurrent event survival data using time-dependent ROC and C-index...
This $622,401 project grant award from the National Institute on Aging's Aging Research Federal Grant Program (CFDA 93.866) supports a multi-year research effort at the University of Southern California to develop advanced artificial intelligence models for analyzing neuroimaging data and identifying modifiable lifestyle factors that influence the progression of Alzheimer's disease and related dementias (ADRD). The key objectives of the project are to: 1) use deep learning and event-based...
This $287,118 Project Grant was awarded on September 1, 2023 by the National Institute on Aging (NIA) under the Aging Research (CFDA 93.866) grant program. The grant will fund the development of techniques to use deep transfer learning and multimodal data, including brain MRIs, genetic information, and cognitive tests, to enable the early detection and forecasting of Alzheimer's disease progression. The University of Massachusetts (UMass), as the prime awardee, will create an end-to-end...
This Project Grant award, provided by the National Institute on Aging under CFDA 93.866 Aging Research, aims to develop an interdisciplinary training program to support 9-10 predoctoral trainees annually in Alzheimer's disease and related dementias (AD/ADRD) research. The $340,632 award to Arizona State University (ASU) will leverage the institution's expertise and partnerships with Mayo Clinic, Banner Alzheimer Institute, Barrow Neurological Institute, and TGen to provide the trainees with a...
This federal Project Grant award, valued at $2,399,431 and effective August 1, 2024, is funded by the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866). The objective is to develop a digital cognitive health resource based on the Boston University Alzheimer's Disease Research Center (BU ADRC) cohort. The grant will leverage the BU ADRC's extensive longitudinal data, including vascular risk factors, biomarkers, and neuropsychological tests, to collect concurrent...
This federal Project Grant award in the amount of $254,250.00 was provided by the National Institute on Aging under the Aging Research program (CFDA 93.866) to New York University School of Medicine. The grant funds a research project to develop a multi-scale model of brain aging and Alzheimer's disease using advanced diffusion MRI techniques. The project aims to create brain charts of quantitative diffusion MRI and mesoscopic MRI markers across the lifespan, and evaluate the sensitivity of...
The National Institute on Aging (NIA) awarded a $791,086 Project Grant under the Aging Research Federal Grant Program (CFDA 93.866) to the Northern California Institute for Research and Education, Inc. (NCIRE) to develop computational models that can predict the presence of non-Alzheimer's disease neuropathological changes (non-ADNC), such as Lewy body disease, TDP-43 proteinopathy, and cerebral amyloid angiopathy, in individuals with Alzheimer's disease neuropathological changes. The project...

The University of Arizona was awarded a $301,417 Project Grant from the National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), to develop innovative models and analytical tools for addressing evidence inconsistency in Alzheimer's disease and Alzheimer's-related dementias (AD/ADRD) research.

Specifically, the project aims to: 1) create novel approaches for modeling evidence inconsistency in network meta-analyses of AD/ADRD interventions, and 2) develop new network meta-regression models that account for uncertainties in study-level summaries of moderator variables. The goal is to advance evidence-based comparative effectiveness research in AD/ADRD by improving methods for synthesizing diverse evidence in the face of data heterogeneity. The project will also deliver an open-source software package to enable applied researchers to accurately utilize the new analytical frameworks. The award period is from May 1, 2025 to April 30, 2027.

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