Project Grant R03AG093512
- Federal Project Grant Award Summary Award Overview Vanderbilt University Medical Center received a $242,489 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) on September 2, 2025, for a project period extending through May 31, 2030. The award supports research examining the proteomic signature of dual decline—the concurrent deterioration of gait and cognitive function in older adults—a condition affecting an estimated 10.2% of the aging...
- Federal Project Grant Award Summary Vanderbilt University Medical Center received a $2.2 million Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) for the five-year period from January 1, 2026 through December 31, 2030. The award supports research investigating mechanistic links between endothelial aging and dementia through development of a novel human induced pluripotent stem cell-endothelial cell (hiPSC-EC) model of aging. The research will...
- Federal Grant Award Summary Vanderbilt University Medical Center received a $3.53 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) awarded September 1, 2025, through August 31, 2029. The research project assesses sex-specific genetic drivers of cerebrovascular disease (CVD) in Alzheimer's disease (AD) brains, addressing the significant underrepresentation of women in AD research despite their disproportionate burden of disease. Using...
- Federal Project Grant Award Summary Vanderbilt University received a $421,250 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) for a two-year project period (July 1, 2026 – June 30, 2028). The award supports research to develop state-dependent engineering of therapeutic functions in reactive astrocytes for Alzheimer's disease treatment. The project will deliver a programmable RNA-based sensing circuit that leverages endogenous ADAR (adenosine...
- Federal Project Grant Award Summary Vanderbilt University Medical Center received a $659,026 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) to develop an innovative diagnostic imaging approach for early detection of Alzheimer's disease (AD). The project, which commenced March 1, 2026, and extends through February 28, 2031, focuses on imaging soluble amyloid beta oligomer (SABO) flow dynamics in the retina using a fluorescein-labeled,...
- Federal Grant Award Summary Vanderbilt University Medical Center received a $149,889 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) beginning September 1, 2025, with a completion date of May 31, 2030. The award supports a discovery-focused research initiative to identify mechanistic associations between epigenetic bone age, frailty measures, and bone imaging findings using artificial intelligence (AI) and deep learning (DL) approaches. The...
- Federal Project Grant Award Summary Vanderbilt University received a $435,875 Project Grant award from the National Institute on Aging (Aging Research program, CFDA 93.866) on May 15, 2026, with completion scheduled for April 30, 2028. The award supports research to characterize the organelle interactome and its role in cellular resilience during aging. The project will employ advanced three-dimensional electron microscopy and artificial intelligence-based image analysis to map organelle...
- Federal Grant Award Summary Vanderbilt University received a $482,800 Project Grant from the National Institute on Aging (Aging Research program, CFDA 93.866) effective February 1, 2026, through January 31, 2031, to conduct research on sphingolipid-dependent remodeling of mitochondria in aging cells. The research addresses mechanisms underlying age-related mitochondrial dysfunction through three integrated research aims utilizing live cell imaging, genetics, and quantitative mass spectrometry...
- Federal Grant Award Summary Award Details: Vanderbilt University received a $105,627.00 F30 Fellowship award from the National Institute on Aging under the Aging Research program (CFDA 93.866) beginning August 5, 2026, with completion scheduled for February 4, 2029. Research Scope: This project grant funds research investigating the dynamics and phenotypic consequences of clonal hematopoiesis caused by mosaic chromosomal alterations (MCAs). The research examines how somatic mutations in...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded Indiana University Indianapolis $607,706 under the Aging Research program (CFDA 93.866) for a five-year project spanning March 1, 2026 through January 31, 2031. The project investigates short-term practice effects (STPE) in individuals with subjective cognitive decline (SCD)—self-reported cognitive changes without objective impairment that may signal early-stage Alzheimer's disease. The research aims to establish whether...
The National Institute on Aging (NIA) awarded Vanderbilt University a $317,000 Project Grant on June 15, 2026, under the Aging Research program (CFDA 93.866) to conduct research examining the relationship between occupational characteristics, labor force participation trajectories across the life course, and cognitive functioning in later life. The research aims to construct parallel trajectories of employment and occupational quality to document how employment histories influence cognitive outcomes in older adults. With a completion date of May 31, 2028, this two-year project addresses the critical public health concern of Alzheimer's disease and related dementias (ADRD), which currently affect approximately 6.5 million Americans over 65, with prevalence expected to double by 2060. The research will analyze work-related factors as modifiable risk factors for cognitive decline by examining how employment quality and labor force engagement interact across the lifespan. Analyses will be stratified by sex to account for differences in employment histories and cognitive aging between men and women, and will assess how educational attainment influences employment trajectories and potentially protects against negative cognitive outcomes associated with lower-quality occupations or limited labor force participation. The project will be performed at Vanderbilt University's Nashville, Tennessee location through the Sponsored Programs Administration division.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $317.0k | 6/8/26 |