Project Grant R03AG093243
- Federal Project Grant Award Summary Washington State University received a $420,750 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective August 5, 2025 through July 31, 2027. The award funds a comprehensive research investigation examining the reciprocal interactions between cognitive performance, beta-amyloid (Aβ) aggregation, transcriptional processing, and sleep disruption in an Alzheimer's disease model. The research employs...
- Federal Grant Award Summary Florida State University's Sponsored Research Administration Division received a $438,915 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective June 1, 2025, through May 31, 2030. The award supports fundamental research to elucidate the genetic and molecular organization of circadian rhythms in mammalian models and humans, with specific focus on...
- Federal Grant Award Summary The University of Florida's Division of Sponsored Research received a $507,214 Project Grant award from the National Institute on Aging (Aging Research program, CFDA 93.866) on February 15, 2026, to conduct systematic research into the role of long-noncoding RNA SLAMR (SLAMR lncRNA) in Alzheimer's disease pathogenesis. This exploratory/developmental R21 grant, with a completion date of January 31, 2028, will deliver peer-reviewed research findings on how SLAMR...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded the University of Florida a $298,296 Project Grant (K02 award mechanism) on September 9, 2025, under the Aging Research program (CFDA 93.866) to support a five-year leadership development initiative extending through May 31, 2030. The award funds a comprehensive training program designed to advance the Principal Investigator's transition from early-stage researcher to a mid-career scientist leading multiple...
- Federal Grant Award Summary Florida State University's Sponsored Research Administration Division received a $301,998 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded April 1, 2026, with completion scheduled for January 31, 2031. The award funds research investigating the effects of memory reactivation on episodic recall and brain function, specifically examining how concurrent and differential reactivation...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded UC San Diego a Project Grant totaling $182,173.00 (awarded March 1, 2026, with completion targeted for February 28, 2031) under the Aging Research program (CFDA 93.866). This research grant supports scientific investigation into the noradrenergic modulation of sleep and its relationship to memory consolidation. The primary deliverables include the development of computational models examining how the locus coeruleus—a...
- Federal Project Grant Award Summary The University of Michigan's Regents received a $107,097 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded September 16, 2025, with completion targeted for June 30, 2027. The award funds research investigating the relationship between sleep disturbances and memory loss in aging populations, addressing a significant public health concern affecting older adults' independence and quality of life....
- Federal Project Grant Award Summary The University of Florida, Division of Sponsored Research, received a $507,371 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) effective June 1, 2025, through March 31, 2030. This award funds research investigating the roles of CASP8 SVA GGGAGA repeat expansions in Alzheimer's Disease (AD). The project will deliver scientific research products examining microsatellite repeat expansions as potential genetic...
- Federal Project Grant Award Summary The University of South Florida received a $412,500 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), awarded June 1, 2025, with a completion date of May 31, 2027. This award funds a comprehensive research initiative to identify novel biomarkers for early diagnosis and prognosis prediction of Alzheimer's disease (AD) through investigation of brain extracellular matrix (ECM) composition changes during normal...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded a $619,099 Project Grant to the University of California, Irvine under the Aging Research program (CFDA 93.866) effective February 1, 2026 through January 31, 2031. This five-year research initiative addresses a critical knowledge gap by investigating longitudinal relationships between Alzheimer's Disease (AD) pathophysiology, local sleep expression, and sleep-dependent memory across preclinical disease stages. The...
Federal Grant Award Summary Florida State University received a $296,232 Project Grant from the National Institute on Aging (Aging Research program, CFDA 93.866) awarded on March 15, 2026, with a completion date of February 29, 2028. The grant funds basic neuroscience research investigating thalamocortical spike dynamics and their relationship to sleep stability and memory consolidation in both normal and Alzheimer's disease-affected brains. The research employs advanced methodologies including optogenetics, pharmacology, and electrophysiology in rat models to elucidate how spike burst patterns in thalamocortical neurons regulate sleep microarchitecture and to test whether increasing spike burst occurrence delays Alzheimer's disease progression and memory deterioration. The project delivers foundational mechanistic knowledge regarding the causal contribution of thalamocortical neurons to sleep stability and the downstream benefits of enhanced sleep stability on memory function and disease progression in Alzheimer's models. These research outcomes are designed to contribute to the development of therapeutic interventions for Alzheimer's disease and related dementias, addressing a significant public health need given the common occurrence of sleep disruption in neurodegenerative diseases. The award supports research training and capacity-building at Florida State University's Sponsored Research Administration Division, positioning the institution as a contributor to the National Institute on Aging's mission of understanding aging processes and preventing or treating age-related neurodegenerative conditions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $296.2k | 3/2/26 |