Project Grant R01NS148386
- Federal Project Grant Award Summary Harvard Medical School received a $151,352 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded August 27, 2026, with completion targeted for February 28, 2029. The award funds fundamental neuroscience research investigating the developmental mechanisms and functional implications of layer 5 cortical circuit...
- Federal Project Grant Award Summary Massachusetts Institute of Technology (MIT) received a $651,069 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded May 2, 2026, with completion targeted for April 30, 2031. The grant funds research to advance spatially multiplexed imaging technology for visualizing complex cellular signaling networks in...
- Federal Project Grant Award Summary Massachusetts Eye And Ear Infirmary received a $131,408 Project Grant from the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) for the period July 1, 2025 through June 30, 2027. This award supports advanced mentored research training focused on investigating maladaptive cortico-amygdalar plasticity following noise-induced hearing loss at the...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Washington University a Project Grant totaling $567,037 beginning August 1, 2025, through July 31, 2030, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This award supports research to characterize the synchronous relationship between peripheral nerve post-injury activity and brain plasticity following traumatic peripheral nerve...
- The federal Project Grant award R21NS140988, totaling $435,875.00, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. This award, with a performance period from Sep 20, 2024 to Aug 31, 2026, will support research by the Trustees of Indiana University (the Awardee) to reveal the functional complexity of cortical vasoactive intestinal polypeptide (VIP)...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded Massachusetts General Hospital a Project Grant of $511,402 effective February 1, 2026, through January 31, 2031, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award supports translational research to develop and validate non-invasive transcutaneous vagus nerve stimulation (NVNS) as a novel neuromodulatory therapeutic...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded Boston Children's Hospital a $489,500 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) for the period July 1, 2025 through June 30, 2027. This R21 exploratory research grant supports a collaborative investigation into stimulus-responsive microproteins in human microglia-like cells, focusing on mRNA translational...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded Massachusetts Institute of Technology (MIT) a Project Grant totaling $1,045,760 (awarded August 1, 2025, with completion by July 31, 2028) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award supports a comprehensive culture change initiative within MIT's Brain and Cognitive Sciences Department to advance research rigor...
- Federal Project Grant Award Summary Harvard Medical School received a $1.2 million Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective August 1, 2025, through July 31, 2033. The award funds an eight-year basic neuroscience research initiative investigating cerebellar circuit organization and function. The research will employ intersectional...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $250,000 Project Grant to the Trustees of Boston University for the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award, obligated on February 23, 2026, with a completion date of January 31, 2031, funds a two-week summer school program on neurovascular imaging across scales in animals and humans, operated by the Boston...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded Massachusetts Eye and Ear Infirmary a Project Grant totaling $452,713 under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) for the period May 14, 2026 through February 28, 2031. The research investigates vasoactive intestinal peptide (VIP) signaling mechanisms in thalamocortical circuit plasticity and learning, with the objective of identifying how VIP release in sensory cortex during learning triggers plasticity at thalamocortical synapses and shapes adaptive cortical remodeling. The research deliverables encompass three integrated aims: defining the cellular and circuit-level mechanisms of VIP signaling that drive thalamocortical plasticity through whole-cell electrophysiology and pharmacological approaches; quantifying temporal dynamics of endogenous VIP release during sensory stimulation and auditory learning using fiber photometry with genetically encoded VIP sensors; and manipulating VIP signaling in vivo to determine its effects on population-level cortical responses, plasticity, and behavioral learning through two-photon photoactivation and calcium imaging in mouse auditory cortex. The research will generate the first direct in vivo measurements of VIP release and establish a mechanistic framework for understanding peptide-based signaling in sensory processing and plasticity, with potential implications for developing therapeutic strategies to enhance circuit reorganization in neurological disorders.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $452.7k | 5/14/26 |