Project Grant R01NS147128
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services National Institutes of Health, awarded $671,988 to the Winifred Masterson Burke Medical Research Institute, Inc. on September 11, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The recipient will conduct research on cross-talk between sarmoptosis and ferroptosis in hemorrhagic stroke, specifically...
- The National Institute of Neurological Disorders and Stroke awarded Yale University $138,664 on February 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the long-term effects of intracerebral hemorrhage on behavior and neuroinflammation. The project employs an in-vivo mouse model of intracerebral hemorrhage using collagenase injection to map microglial activation and behavioral changes following stroke. Research...
- The National Institute of Neurological Disorders and Stroke, a component of the Department of Health and Human Services National Institutes of Health, awarded the University of Cincinnati $654,628 on March 6, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to characterize the peripheral and immune-cell proteome in intracerebral hemorrhage patients and identify biomarkers and mechanisms associated with vascular cognitive...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services National Institutes of Health, awarded The Medical University of South Carolina $100,228 on December 16, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research on complement-mediated mechanisms of injury and repair in germinal matrix hemorrhage, a leading neurological injury of prematurity....
- The National Institute of Neurological Disorders and Stroke, a component of the Department of Health and Human Services National Institutes of Health, awarded The Leland Stanford Junior University $432,647 on May 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate ferroptosis as a mechanism of post-hemorrhagic hydrocephalus following severe neonatal intraventricular hemorrhage. The research addresses the absence of...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $198,164 to Weill Medical College of Cornell University on September 15, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the role of heme in oxidative modification of mRNA in neurodegenerative disease. The research examines how heme binds to G-quadruplex sequences...
- The National Institute of Neurological Disorders and Stroke, a component of the Department of Health and Human Services National Institutes of Health, awarded $462,000 to Albert Einstein College of Medicine on April 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) for a Project Grant titled "Inhibition of Fibrinogen Reduces Brain Injury and Hydrocephalus in Premature Neonates with Intraventricular Hemorrhage." The...
- The National Institute of Neurological Disorders and Stroke awarded Yale University $462,151 on May 19, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate genetic mosaicism and molecular mechanisms in human cerebral cavernous malformations. The project focuses on familial cerebral cavernous malformation, a cerebrovascular disease characterized by vascular lesions in the central nervous system that cause seizures and...
- The National Institute of Neurological Disorders and Stroke awarded the University of Texas Health Science Center at Houston $429,000 on April 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853, Assistance Listing R21NS142863). The award funds research into the role of skull bone marrow neutrophils in delayed neurological decline following aneurysmal subarachnoid hemorrhage. The project investigates why skull neutrophils respond...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services, awarded Drexel University $547,255 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds investigation of the functional organization of descending neuron networks that control collision-avoidance behavior. Using electron microscopy connectomes of the central nervous system at synaptic...
The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded Yale University $667,613 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research examining ferroptosis—iron-induced programmed cell death—in erythrocytes within intracerebral hemorrhage hematomas. The project investigates how heme induces erythrocyte ferroptosis, leading to cell swelling and membrane pore formation, and tests pharmacological inhibitors to reduce or delay erythrocyte lysis and improve outcomes following intracerebral hemorrhage. Performance occurs in New Haven, Connecticut, with a period of performance from September 1, 2026, through May 31, 2031. The award is classified as a Project Grant, a research assistance type supporting investigator-initiated fundamental inquiry in neuroscience reviewed on scientific merit by peer technical panels and the National Advisory Neurological Disorders and Stroke Council.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $667.6k | 9/1/26 |