Project Grant R01NS146895
- The National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, awarded Oregon Health & Science University $858,000 on September 24, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds in vivo investigations of astrocyte-oligodendrocyte interactions using molecular, genetic, cellular, and proteomic tools to define astrocyte-oligodendrocyte myelin interactions at the...
- The National Institute of Neurological Disorders and Stroke awarded Oregon Health & Science University $247,702 on December 1, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate neuronal and glial mechanisms regulating PAIR1 local pruning. The research examines how neurons and glia communicate during synaptic pruning—the process by which developing nervous systems eliminate excess neuronal connections. Using...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services, awarded Oregon Health & Science University $429,000 on August 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research into the molecular pathways driving neurodegeneration, specifically examining how roundabout (ROBO) receptors regulate axon degeneration following nervous system injury....
- The National Institute of Neurological Disorders and Stroke awarded Oregon Health & Science University $126,122 on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate how astrocytes regulate neuronal circuits through calcium signaling and neuromodulation. The recipient will conduct research on astrocyte gating mechanisms, specifically exploring how arousal-associated tyramine cues alter astrocyte...
- The National Institute of Neurological Disorders and Stroke awarded Oregon Health & Science University $536,121 on May 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) for Project Grant R01NS144584. The award funds research into the metabolic basis for oligodendrocyte-vascular interactions in white matter development and injury, with focus on neonatal white matter injury resulting from hypoxia-ischemia in preterm and...
- Federal Project Grant Award Summary Oregon Health & Science University (OHSU) received a $420,744 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, awarded June 1, 2025, with a completion date of May 31, 2027. This research project focuses on profiling adenosine-to-inosine (A-to-I) editing in single neurons, a post-transcriptional RNA modification...
- The National Institute of Neurological Disorders and Stroke awarded Oregon Health & Science University $429,000 on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop and optimize a chemical-genetic method for rapid, cell type-specific labeling of newly synthesized proteins in nervous system tissue. The project, titled "Rapid and Cell Type Specific Nascent Proteome Labeling in the Nervous System,"...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $594,435 to Oregon Health & Science University on August 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to conduct research on pericyte phenotypic switching in diabetic post-stroke cognitive impairment. The project, R01NS146933, investigates the cellular and molecular...
- The National Institute of Neurological Disorders and Stroke awarded Oregon Health & Science University $619,833 on August 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to decode PARP7 marylation-ubiquitylation crosstalk in neuronal health and disease. The research will identify neuronal PARP7 substrates and marylation sites using chemical-genetic proteomics; establish the enzymatic machinery (writers, extenders, and...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $711,256 to the University of Arizona on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research defining how neurons drive outcomes in CNS toxoplasmosis caused by Toxoplasma gondii. The research addresses a mechanistic gap in understanding neuron-T....
The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services, awarded Oregon Health & Science University $507,491 under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) on August 12, 2026. The award funds investigation into the mechanistic basis of astrocyte-neuron signaling during neuronal remodeling in the developing brain. The research uses Drosophila models to understand how astrocytes promote the selective elimination of excess synapses, axons, dendrites, and neurons—a process essential for nervous system development but disrupted in autism spectrum disorder, schizophrenia, and epilepsy. The work characterizes four neuronal cell types undergoing either cell death or local pruning, defines precise changes in cell architecture and synaptic connections in each type, and explores the cellular and molecular mechanisms driving remodeling events. Performance occurs in Portland, Oregon. The period of performance extends from the award date through July 31, 2031. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $507.5k | 8/12/26 |