This $536,617 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to understand the mechanisms of neural regeneration in model organisms. The primary awardee, Oregon Health & Science University, will conduct experiments using planarians and zebrafish to investigate how adult neural stem cells can regenerate neural tissue and restore...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $420,744 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Oregon Health & Science University (OHSU). The funding will support the development of a methodology to simultaneously analyze adenosine-to-inosine (A-to-I) RNA editing sites in targeted RNAs using long-read sequencing and characterize specific neuronal cell subtypes via short-read...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $2,503,949 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Rockefeller University. The grant, awarded on May 1, 2025, supports a research project titled "Applying RNA Logic in Space and Time to Neurologic Disease". The project aims to develop new techniques and concepts to discover therapeutic targets for neurological diseases by studying...
This $563,343 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under CFDA 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders, supports research conducted by New York University (NYU) to investigate the physical, molecular, and cellular mechanisms underlying tissue guidance and tissue splitting during nervous system development. The research uses the posterior lateral line primordium migration in zebrafish as...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $481,126 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of Chicago. The grant supports research to structurally and functionally characterize how the UNC-6/Netrin axon guidance cue complexes with the UNC-5 receptor to generate repulsive signals for neuronal wiring, in contrast to the UNC-6-UNC-40/DCC attractive complexes. The...
This Project Grant award, valued at $481,250.00 and provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop a synthetic biological system to manipulate subcellular RNAs and proteins in growth cones or synapses of subtype- and context-specific neurons. The goal is to enable unique forms of subcellular functional investigation in subtype- and...
The University of Oregon (UO) received a Project Grant award of $405,625 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The goal of this 2-year project is to identify the genes that coordinate the development of both electrical and chemical synapses in the vertebrate nervous system, using the zebrafish Mauthner circuit as a model system....
This federal Project Grant award of $426,650 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) aims to develop a hybrid strategy for rapidly generating region-specific neural progenitor cells and oligodendrocytes from human pluripotent stem cells. The grant, awarded to Trustees of Tufts College, will focus on leveraging Sox10 transcription factor induction to efficiently...
This Project Grant award of $385,500 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports the development of a novel inducible and multiplexed dual gene regulation CRISPR system to study neuronal activity and regeneration. The award will fund research at The Leland Stanford Junior University (Stanford University) to engineer a system capable of simultaneous...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $397,500.00 to the Massachusetts Institute of Technology (MIT) to study the fundamental principles linking neurodevelopmental processes to the functional organization of neural circuits that could enable network-scale regeneration. The 5-year award, starting on May 1, 2025,...