Project Grant K99NS138586
- This Project Grant award of $426,313, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), supports research at The Johns Hopkins University to investigate the signaling pathways that disrupt neurofilament (NF) phosphorylation dynamics and lead to NF hyperphosphorylation, a pathology associated with neurodegenerative diseases such as amyotrophic lateral...
- This $270,434 federal Project Grant award, funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate the mechanistic link between spatiotemporal regulation of mRNA and neuronal remodeling during morphogenesis. The principal investigator will use Drosophila mushroom body and dendritic arborization neurons as models to study the...
- This federal Project Grant award of $401,000.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research to map and model multiscale lateral interactions in the cerebral cortex that are critical for processing complex sensory information. The project aims to directly probe local lateral interactions in cortical circuits, determine...
- This federal Project Grant award of $377,602 was made on September 1, 2025 by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award supports research by the Georgia Tech Research Corporation, Office of Sponsored Programs to investigate the circuit mechanisms of sensorimotor predictive processing for active touch. The project aims to enhance understanding of...
- This federal Project Grant award for $1,042,170.00, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to apply computational modeling to the analysis of intracranial recording and stimulation data from the human brain. The key objectives are to 1) dissect the neural activity patterns underlying electrophysiology recordings, and 2)...
- This federal Project Grant award of $434,769 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to investigate the role of invadosomes, actin-based protrusions, in axon guidance and growth cone navigation during nervous system development. The research aims to elucidate how EGF ligands promote invadosome formation and function, leading to extracellular...
- The Johns Hopkins University received a $1,490,248 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The award supports a 3-year research project titled "Cortical Circuit Dynamics Underlying Multisensory Decision Making." The project aims to investigate how the brain integrates visual, vestibular, and kinesthetic...
- This federal Project Grant award, valued at $147,486, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The purpose of this award is to investigate the function of a ciliary protein in neural development, with a focus on uncovering novel molecular mechanisms involved in synapse formation that may be relevant to neurological disorders. Using C. elegans as...
- This Project Grant award of $100,272.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to understand how axon guidance is regulated in the mature nervous system. The research aims to identify molecular and cellular mechanisms that regulate axon regeneration and guidance, with a focus on using the Caenorhabditis elegans model system to study an...
- This federal Project Grant award of $629,796 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award aims to track, quantify, and localize key metabolic pathways that regulate brain growth during development. Specifically, the project will investigate two critical metabolic switches in the developing mouse brain: (1) a shift from glycolytic to...
This federal Project Grant award of $120,987.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at The Johns Hopkins University to investigate the molecular mechanisms underlying interstitial axon branching in the mammalian cerebral cortex. The research aims to gain a better understanding of how laminar-specific innervation is established in the cerebral cortex, a critical process for sensory processing, motor skills, learning, and memory. Key areas of investigation include the role of specific intracellular signaling pathways and cell surface molecules in regulating interstitial axon branching, with the goal of advancing scientific knowledge in this important area of neuroscience. The award period is from August 4, 2025 to July 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $121.0k | 8/1/25 |