Project Grant R01NS139886
- This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) provides $325,000.00 to the Massachusetts Institute of Technology (MIT) to develop 3D-integrated micro-photometer chips for monitoring neural dynamics in the brain. The project aims to elucidate the effects of beam collimation, compact chip size, and mechanical flexibility of implantable optoelectronic probes on the quality of in vivo deep-brain fluorescence recordings. The research team plans...
- The Johns Hopkins University was awarded a $2,008,605 Project Grant under the National Institute of Neurological Disorders and Stroke's 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The grant funding will support the development of an "Autonomous Rapidly Adaptive Multiphoton Microscope for Neural Recording and Stimulation." This adaptive multiphoton microscope system will leverage hybrid volumetric scanning,...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $4,095,511 Cooperative Agreement under the "21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative" (CFDA 93.372) to The Children's Hospital Corporation (doing business as Boston Children's Hospital). The funding will support the development of a high-throughput brain connectomics solution by integrating automated section collection and handling with advanced...
- The National Institutes of Health National Institute of Neurological Disorders and Stroke awarded $1,852,675 under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies program (CFDA 93.372) to the University of California, Los Angeles from August 1, 2022 to July 31, 2025. The award will support the development of light field tomographic microscopy for kilohertz volumetric imaging of neuronal action potentials in awake behaving mice. Specifically, the...
- The University of Minnesota was awarded a $3,972,414 Project Grant from the National Institute of Neurological Disorders and Stroke within the Department of Health and Human Services to develop an electro-optical multiphoton microscope. The microscope will leverage advances in electro-optical beam deflection to enable random-access multiphoton interrogation of neurons and synapses with sub-microsecond access times. This will allow neuroscientists to collect the simultaneous recordings needed...
- The Regents of the University of Minnesota received a $325,450.00 Project Grant award on August 5, 2025 from the National Institute of Neurological Disorders and Stroke (NINDS) under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative program (CFDA 93.372). The grant will fund the development of ultra-high-speed voltage imaging technology to record the neural activity of Purkinje cells in the cerebellum of awake, behaving mice. The...
- The Regents of the University of Michigan received a $137,586 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The grant funds the development of a reconfigurable neural interface platform that can integrate multiple sensor modalities, including electrophysiological recording, neurostimulation, and physiochemical...
- The National Institutes of Health National Institute of Neurological Disorders and Stroke awarded $3.6 million under the 21st Century Cures Act Brain Research through Advancing Innovative Neurotechnologies program (CFDA 93.372) to Stanford University. The project grant will support development of a noninvasive, dynamically programmable in vivo light source for rapid brain-wide optogenetic screening. Specifically, the awardee aims to develop mechanoluminescent nanoparticles with distinct emission...
- The Massachusetts Institute of Technology (MIT) was awarded a $1,045,760 Project Grant by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The 3-year grant, which runs from August 1, 2025 to July 31, 2028, aims to transform research rigor and transparency in MIT's Brain and Cognitive Sciences (BCS) department through a comprehensive culture change approach developed in...
- This $556,525 Project Grant was awarded on June 1, 2025 by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The grant will fund the development, testing, and dissemination of micro-LED optoelectrode platforms for monitoring and perturbing targeted neurons in multiple local brain circuits. These platforms will provide a new tool for analyzing the dynamic...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $2,724,344 Project Grant under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative to the Massachusetts Institute of Technology (MIT). The grant, awarded on August 1, 2025, supports the development of two new high-speed image sensor technologies: These novel image sensors, based on MIT's proprietary "pixel-wise programmable exposure" CMOS architecture, are designed to overcome the spatial-temporal resolution and signal-to-noise ratio limitations of current imaging systems. The goal is to enable high-speed fluorescence imaging capable of resolving single neural spike events in freely behaving animal models, supporting advancements in neuroethology research.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.4m | 8/7/25 | ||
| Not listed | $1.4m | 7/30/25 |