Project Grant R01NS138353

Award Date 6/27/25
Completion Date 3/31/30
Dollars Obligated $435K
Federal Grant Program
93.853
Assistance Type
Project Grant
Place of Performance
Madison, WI 53715, USA
Similar Awards
This $563,343 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under CFDA 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders, supports research conducted by New York University (NYU) to investigate the physical, molecular, and cellular mechanisms underlying tissue guidance and tissue splitting during nervous system development. The research uses the posterior lateral line primordium migration in zebrafish as...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $481,126 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of Chicago. The grant supports research to structurally and functionally characterize how the UNC-6/Netrin axon guidance cue complexes with the UNC-5 receptor to generate repulsive signals for neuronal wiring, in contrast to the UNC-6-UNC-40/DCC attractive complexes. The...
This $210,600 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will fund research to investigate how Wnt signaling mediates the formation of repair cells from Schwann cells in the peripheral nervous system. The primary goals are to 1) provide functional tests of the role of Wnt receptors and ligands in controlling repair cell...
This Project Grant award, valued at $481,250.00 and provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop a synthetic biological system to manipulate subcellular RNAs and proteins in growth cones or synapses of subtype- and context-specific neurons. The goal is to enable unique forms of subcellular functional investigation in subtype- and...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $576,841.00 to The Trustees of the University of Pennsylvania to conduct research on "Mechanisms of DCC Receptor Signaling in Neuronal Morphogenesis". The research aims to define how the DCC receptor protein coordinates signaling pathways that regulate the...
This Project Grant award of $644,008.00 was made by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The grant supports research to determine the role of the lipid transport protein NIR2 in regulating phosphoinositide signaling at endoplasmic reticulum-plasma membrane (ER-PM) contact sites, and its impact on dendrite development in mouse cortical...
The federal Project Grant award R01NS139914 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The $582,883 award, effective December 1, 2024 through November 30, 2029, supports research by the Regents of the University of California at Riverside to study the role of CAS adaptor proteins in cortical axon pathfinding and the development of proper neural...
This $536,617 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to understand the mechanisms of neural regeneration in model organisms. The primary awardee, Oregon Health & Science University, will conduct experiments using planarians and zebrafish to investigate how adult neural stem cells can regenerate neural tissue and restore...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $2,503,949 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Rockefeller University. The grant, awarded on May 1, 2025, supports a research project titled "Applying RNA Logic in Space and Time to Neurologic Disease". The project aims to develop new techniques and concepts to discover therapeutic targets for neurological diseases by studying...
This federal Project Grant award of $454,424.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will support research to characterize cellular and molecular mechanisms of Schwann cell demyelination and identify factors that promote peripheral remyelination. The research will utilize a novel larval zebrafish model to visually assess nerve damage and repair over...

This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is funding research to investigate the regulation of invadosome-mediated peripheral axon guidance by ErbB signaling. The $434,769 award, made on June 27, 2025, will support the University of Wisconsin-Madison's efforts to better understand the molecular mechanisms that control axon guidance and growth cone protrusions across three-dimensional tissues and basement membranes. The research aims to elucidate the specific receptors, ligands, and signaling pathways that promote invadosome formation and maturation, and their role in enabling peripheral axons to exit the spinal cord. This work is expected to advance scientific understanding of neuronal development and guidance, with potential implications for addressing neurological disorders.

Generated 8/5/25, 5:44 AM