Project Grant R01NS137650

Award Date 12/1/24
Completion Date 11/30/29
Dollars Obligated $580K
Federal Grant Program
93.853
Assistance Type
Project Grant
Place of Performance
Stanford, CA 94305, USA
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The goal of the 5-year project is to examine how thalamic subregions, specifically the anterior nucleus of the thalamus (ANT) and pulvinar, are connected to other brain structures, how seizures engage these thalamic areas differently, and the spatiotemporal dynamics of ANT activity during memory encoding tasks. The research aims to create a comprehensive map of cortico-thalamo-cortical connections, determine thalamic routes of seizure propagation, and provide mechanistic insights into the role of the ANT in human memory processes. This knowledge is expected to inform future personalized treatment strategies for refractory epilepsy patients.

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