This $1,319,282 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program will fund research to develop effective methods for forecasting seizures in individuals with epilepsy. The key goals are to: (1) establish biochemical signatures in saliva that correlate with periods of increased seizure likelihood, and (2) leverage these...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $426,250 Project Grant under CFDA 93.853, Extramural Research Programs in the Neurosciences and Neurological Disorders, to the Regents of the University of Minnesota, Office of Sponsored Projects Administration. This 2-year grant will fund research using cutting-edge voltage imaging to examine how interactions between specific neuronal circuit elements in the hippocampus relate to the development of temporal lobe...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $555,499 project grant (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to The Leland Stanford Junior University for a 5-year period from December 1, 2024 to November 30, 2029. The grant supports research to develop novel, non-invasive behavioral biomarkers for predicting chronic seizures and mortality in mouse models of temporal lobe epilepsy and Dravet syndrome. The project...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $698,684 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Washington University in St. Louis. The grant, which runs from May 1, 2024 to April 30, 2029, will fund research to identify prospective biomarkers of epilepsy susceptibility in very preterm infants with intraventricular hemorrhage. The key products and services to be delivered include:...
This $225,599 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will fund research on the contributions of sex chromosomes and gonadal hormones in shaping sex differences in epilepsy. The studies will apply a unique mouse model to determine the roles of sex chromosomes and gonadal hormones in acute seizure susceptibility, seizure-induced...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program provides $1,848,029 to study the regulation of the SCN8A sodium channel and its impact on pediatric epilepsy. The project aims to: Evaluate the role of SCN8A exon 5 alternative splicing on brain activity, neuronal excitability, and seizure susceptibility. Determine the efficacy of...
This federal Project Grant award, valued at $234,276, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant will support a 5-year research study conducted by the University of California, San Diego to develop advanced methods for predicting outcomes of epilepsy surgery using functional MRI (fMRI) data. The research aims to identify associations...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $438,836 Project Grant (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to The Trustees of the Stevens Institute of Technology on August 15, 2024. The grant supports the development of a unified framework called "Electrophysiological Networks Imaging" (ENI) to model epileptic electrophysiological brain networks using a simultaneous multimodal measurement of scalp...
This federal Project Grant award, ID R01NS136297, is funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The $690,763 grant, awarded on Dec 1, 2024, aims to optimize neuromodulation therapies for epilepsy by identifying key factors that determine patient response to Responsive Neurostimulation (RNS) treatment. The three main objectives are: 1) utilizing...
This $451,000 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support computational behavioral phenotyping and large-scale drug screening of 12 different zebrafish models representing genetic epilepsies. The research aims to better understand the mechanisms behind these intractable neurological conditions and identify potential...