This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is funding a research project titled "The Role of Red Blood Cell in Stroke-Related Hyperglycemia" at The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH). The $1,267,716 award, with a project period from August 1, 2024 to May 31, 2029, aims to investigate the role of red blood cells in stroke-related hyperglycemia through translational research and mechanistic studies. Key objectives include characterizing acute hyperglycemia-related red blood cell alterations in clinical stroke patients, exploring the mechanisms of these red blood cell changes in in vitro hyperglycemic models, and validating the findings in an acute hyperglycemic stroke mouse model. The project seeks to develop a comprehensive understanding of the effects of acute hyperglycemia on red blood cells and their consequences on vascular function, with the goal of enhancing clinical care and improving patient outcomes.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $422.6k | 4/25/25 | ||
| Not listed | $422.6k | 7/30/24 | ||
| Not listed | $422.6k | 7/30/24 |