The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $2,359,174 Project Grant under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to conduct research on the biophysical mechanisms of cortical microstimulation. The project aims to develop a more mechanistic understanding of how direct local electrical stimulation...
This federal Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under CFDA Program 93.865 Child Health and Human Development Extramural Research, provides $185,713 to the Rehabilitation Institute of Chicago (doing business as Shirley Ryan AbilityLab) to study neuromodulatory strategies targeting cortical and spinal pathways to facilitate paretic leg motor control during walking in individuals with stroke. The key objectives are...
This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the federal Child Health and Human Development Extramural Research program (CFDA 93.865), will provide $414,376 to the University of North Carolina at Chapel Hill to study the modulation of beta oscillatory rhythms in stroke patients to promote corticomuscular circuit function. The key objectives are to determine the modulatory effects of beta-burst repetitive...
The University of Arizona was awarded a $1,384,314 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) by the National Institutes of Health (NIH) to develop novel response-contingent neuromodulation devices. The goal is to electrically modulate neural circuit plasticity in order to promote motor recovery and rebalance the pain circuitry for individuals with spinal cord injuries (SCIs). The 3-year project, starting on September 1, 2025, will assess whether motor-contingent...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under CFDA Program 93.853 "Extramural Research Programs in the Neurosciences and Neurological Disorders", provides $427,625.00 to study whether electrical stimulation can enhance the capacity of neural stem cell transplants to improve recovery from chronic spinal cord injury. The primary goal is to determine if electrical stimulation supports the survival and differentiation of stem...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $898,025 to the University of Cincinnati to evaluate the use of transcutaneous spinal direct current stimulation (tsDCS) to modulate spinal interoceptive pathways (SIPs) and their role in Major Depressive Disorder (MDD) symptoms. The research aims to assess tsDCS-induced changes in laser-evoked potentials (LEPs) as neural markers of SIPs engagement...
The National Institutes of Health National Institute of Neurological Disorders and Stroke awarded an $11.2 million project grant to the University of Pittsburgh to define the mechanisms of pain relief associated with dorsal root ganglion and spinal cord stimulation. This three-year grant will support research under the Drug Abuse and Addiction Research Programs (CFDA 93.279) to advance understanding of neuromodulatory devices for chronic pain treatment. The University will conduct preclinical...
This $764,646 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support a 3-year research project titled "Advancing Non-Invasive Brain Stimulation: A Comprehensive Study of Temporal Interference Mechanisms (CNS-STIM)". The project aims to bridge gaps in understanding how the innovative non-invasive brain stimulation technique...
This $1,365,844 Cooperative Agreement award, granted by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports a Phase 2 clinical trial to determine the cognitive and motor effects of theta burst deep brain stimulation (DBS) of the subthalamic nucleus in Parkinson's disease patients. The award aims to evaluate whether short-term and chronic theta burst STN...
This $450,213 National Science Foundation project grant will fund research at Loyola University of Chicago to develop a fundamental theory for using electrical modalities to enhance physical rehabilitation outcomes. Specifically, the grantee will investigate how best to use neuromodulation techniques to improve the results of neurorehabilitation by incorporating different electrical stimulation sequences. The research aims to provide insights into how peripheral nerve stimulation can assist axon...