Project Grant R01MH142405
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a Project Grant of $121,933.00 to the University of California, San Diego under the Mental Health Research Grants program (CFDA 93.242) for the period of June 1, 2025 through May 31, 2027. This research project will deliver scientific investigation into compartment-specific synaptic organization and plasticity in layer 2/3 pyramidal neurons during learning in behaving animals. The research employs cutting-edge...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Regents of the University of California, San Francisco $800,384 under the Mental Health Research Grants program (CFDA 93.242) on March 10, 2026, for a project titled "Molecular and Functional Dissection of Prefrontal-Hippocampal Long-Range Inhibition." This Project Grant supports basic neuroscience research investigating the mechanisms through which the prefrontal cortex exerts top-down control...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $150,104 Project Grant to The Regents of the University of California, San Francisco under the Mental Health Research Grants program (CFDA 93.242) for the period March 1, 2026 through October 31, 2028. This award supports basic neuroscience research investigating the role of myelin plasticity in long-term memory formation and recall. The project aims to advance understanding of cellular mechanisms underlying...
- Federal Grant Award Summary New York University School of Medicine received a $1.34 million Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) on September 19, 2025, with a completion date of August 31, 2028. The award supports research and development of a novel noninvasive neuroengineering platform utilizing molecularly engineered nanocrystals for precise modulation of neural structures. The research centers...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the Regents of the University of Michigan a $3.97 million Project Grant (CFDA 93.242 - Mental Health Research Grants) effective August 1, 2025, through July 31, 2028, to develop a scalable high-plex pipeline for whole-brain proteomics profiling. The project addresses a critical gap in neuroscience research by creating a comprehensive proteomics atlas of the mammalian brain, complementing existing transcriptomics...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded $818,253 to The Regents of the University of California, San Francisco under the Mental Health Research Grants program (CFDA 93.242) beginning July 1, 2025, and extending through April 30, 2030. This Project Grant supports a five-year research investigation examining neuromodulatory system abnormalities in late-life depression (LLD), with specific focus on the associations between structural and functional brain...
- Federal Project Grant Award Summary The University of California, San Diego received a $415,664 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded on March 15, 2026, with a completion date of December 31, 2030. This award supports a research project investigating the dissociable roles of distinct orbitostriatal circuits in value-based decision-making. The research employs advanced neuroscientific...
- Federal Grant Award Summary The Scripps Research Institute received a $878,601 Project Grant award from the National Institute of Mental Health under the Mental Health Research Grants program (CFDA 93.242), effective April 1, 2026, with completion targeted for December 31, 2030. This collaborative research program delivers advanced neuroscience research services focused on understanding how neural circuits in the mammalian brain reorganize to encode new memories. The project combines...
- Federal Grant Award Summary New York University received a $633,438 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) on June 16, 2025, with a completion date of March 31, 2030. The award supports research on data-driven control of primate prefrontal neural activity using patterned microstimulation. The project addresses a critical gap in neuroscience and neuroengineering by developing a data-driven framework for...
- Federal Grant Award Summary Rockefeller University received a $768,000 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded on September 20, 2025, with a completion date of June 30, 2030. The grant funds the development of an advanced optical imaging platform designed to enable high-fidelity voltage imaging of large neuronal populations in vivo. The project extends the institution's previous work on calcium...
The National Institute of Mental Health (NIMH) awarded University of California, Berkeley a Project Grant totaling $1,170,843 under the Mental Health Research Grants program (CFDA 93.242), effective April 1, 2026 through February 28, 2029. The award supports research on optical control of deep synaptic signaling, advancing fundamental neuroscience understanding of synaptic plasticity and memory storage mechanisms in the mammalian brain. The project delivers innovative research utilizing chemical optogenetics and synthetic photoswitches to enable precise light-activated control of neurotransmitter receptors at specific synaptic compartments and neuronal connections, addressing critical gaps in measuring and manipulating synaptic strength during learning in intact brains. The research products generated through this award include development and validation of enhanced optical control technologies applicable to ionotropic and G protein-coupled receptors, alongside empirical findings characterizing receptor-specific synaptic transmission and neuromodulation in awake behaving animal models. These methodological advances and associated data contribute to the broader NIMH mission of transforming understanding and treatment of mental illnesses through basic neuroscience research, with potential applications to psychiatric condition research and therapeutic development.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.2m | 3/13/26 |