Project Grant R01MH142350
- The National Institute of Mental Health awarded the University of Alabama at Birmingham $185,609 on August 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct epidemiologic modeling identifying optimal evidence-based interventions to reduce HIV incidence in Alabama. The award funds mathematical modeling work embedded within a NIAID-funded R01 effectiveness-implementation trial evaluating three combination evidence-based interventions in the southwestern region of...
- The National Institute of Mental Health awarded the University of Alabama at Birmingham $409,750 on March 15, 2026, under the Mental Health Research Grants program (CFDA 93.242) to determine the role of localized dopamine signals in learning. The research uses two-photon microscopy and genetically encoded sensors to simultaneously track dopamine release and neuronal activity in real-time as mice perform a neuroprosthetic control task. The work investigates whether dopamine shapes learning at the...
- The National Institute of Mental Health awarded the University of Alabama at Birmingham $678,550 on July 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct a randomized clinical trial evaluating the Advanced HIV Re-engagement in Care (ARC) intervention in Zambia. ARC is a package of evidence-based, theory-informed elements delivered by supervised community health workers during hospitalization and the post-discharge period to improve outcomes for people with...
- The National Institute of Mental Health awarded The General Hospital Corporation (Massachusetts General Hospital) $824,404 on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop machine learning models that integrate clinician-conducted suicide risk assessments with electronic health record data to improve prediction of suicidal behavior and guide precision interventions in outpatient behavioral health settings. The research leverages routine clinical...
- The National Institute of Mental Health awarded the University of Pittsburgh $1,004,971 through the Mental Health Research Grants program (CFDA 93.242) on April 8, 2026, to develop a platform for measuring and analyzing brain activity, cognitive states, behavior, and physiology during multiday neural recordings in individuals undergoing surgical treatment for epilepsy. The project will integrate wearable technology and artificial intelligence for behavioral and physiological monitoring alongside...
- The National Institute of Mental Health awarded the University of Alabama at Birmingham $1.809 million on June 5, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop novel preclinical models of neuroHIV that incorporate antiretroviral therapy suppression dynamics. The award funds development of next-generation neuroHIV models composed of autologous peripheral human immune cells, relevant human glial cell types, and an intact blood-brain barrier in the context of...
- The National Institute of Mental Health awarded the University of Alabama at Birmingham $2,590,839 on September 18, 2025, under the Mental Health Research Grants program (CFDA 93.242) to develop and evaluate PROTECT AL, a dashboard and implementation framework designed to optimize HIV pre-exposure prophylaxis (PrEP) utilization across Alabama. The award funds a multi-phase mixed-methods implementation study that refines a performance measurement dashboard with clinic-level PrEP coverage...
- The National Institute of Mental Health awarded the University of Alabama at Birmingham $726,339 on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct a hybrid randomized effectiveness-implementation trial of THRIVE, a recovery-focused suicide prevention intervention for crisis stabilization centers. THRIVE is a suicide recovery and care transitions program combining a belonging, giving, and recovery psychotherapy group during crisis stabilization...
- The National Institute of Mental Health awarded the University of Alabama at Birmingham $616,868 on August 12, 2026, under the Mental Health Research Grants program (CFDA 93.242) to investigate neural circuit mechanisms underlying postpartum social cognitive impairment induced by adolescent stress. The recipient will develop and deploy a mouse model to explore how early life stress—specifically mild social isolation during late adolescence—affects postpartum behaviors and cognition. The research...
- The National Institute of Mental Health awarded the University of Alabama $170,381 on July 15, 2026, under Mental Health Research Grants (CFDA 93.242), a Project Grant (R03MH138952) to investigate the relationship between habitual physical activity levels and model-based decision-making in adults with post-traumatic stress disorder, with a focus on endocannabinoid biomarkers as potential mediators of this relationship. The research will examine whether sustained physical activity patterns...
The National Institute of Mental Health awarded the University of Alabama at Birmingham $786,444 on August 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop an artificial intelligence-based decision support system for predicting and preventing return emergency department visits among mental health patients. The project will develop a large language model system to automatically extract mental health emergency department return risk factors from clinical notes, using retrieval-augmented generation techniques to identify key clinical, operational, and social determinant factors such as medication adherence and poor outpatient follow-up. The system's accuracy will be validated through manual chart reviews by clinical experts and multisite validation. The project will also develop explainable machine learning models to predict emergency department return among mental health patients, addressing a gap in validated prediction models designed specifically for this population, which research indicates have a 4.7 times higher rate of frequent emergency department use compared to non-mental health patients. The work is performed in Birmingham, Alabama, with a period of performance extending from August 1, 2026, through April 30, 2031. This is a Project Grant, the standard assistance type under NIMH's research portfolio.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $786.4k | 7/29/26 |