Project Grant K01MH140640
- The National Institute of Mental Health awarded the University of Alabama at Birmingham $2,590,839 on September 18, 2025, under the Mental Health Research Grants program (CFDA 93.242) to develop and evaluate PROTECT AL, a dashboard and implementation framework designed to optimize HIV pre-exposure prophylaxis (PrEP) utilization across Alabama. The award funds a multi-phase mixed-methods implementation study that refines a performance measurement dashboard with clinic-level PrEP coverage...
- The National Institute of Mental Health awarded the University of Alabama at Birmingham $1.809 million on June 5, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop novel preclinical models of neuroHIV that incorporate antiretroviral therapy suppression dynamics. The award funds development of next-generation neuroHIV models composed of autologous peripheral human immune cells, relevant human glial cell types, and an intact blood-brain barrier in the context of...
- The National Institute of Mental Health awarded the University of Alabama at Birmingham $786,444 on August 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop an artificial intelligence-based decision support system for predicting and preventing return emergency department visits among mental health patients. The project will develop a large language model system to automatically extract mental health emergency department return risk factors from clinical notes,...
- The National Institute of Allergy and Infectious Diseases awarded the University of Alabama at Birmingham $223,500 on July 22, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate how menopause and menopausal hormone therapy alter immune determinants of HIV-1 susceptibility in cervical mucosa. The research integrates an ex vivo cervical explant tissue model to study infection with transmitted/founder HIV-1 strains, high-parameter spectral flow...
- The National Institute of Mental Health awarded the University of Alabama at Birmingham $396,627 on September 10, 2025, under the Mental Health Research Grants program (CFDA 93.242) to evaluate the Healthy Families-PREP intervention, a counseling and adherence-support program designed to promote oral tenofovir-based PrEP use among periconception, pregnant, and postpartum women in rural Uganda to reduce HIV incidence. The project builds on pilot data from a Ugandan HIV care clinic where 131 women...
- The National Institute of Mental Health awarded The Johns Hopkins University $149,190 on August 2, 2026, under the Mental Health Research Grants program (CFDA 93.242) to identify intervention opportunities in the continuum of cognitive impairment among persons aging with HIV. The research will estimate the proportion of cognitive impairment cases among people with HIV potentially attributable to psychosocial and behavioral risk factors, prioritizing those interventions that could prevent the...
- The National Institute of Mental Health awarded the University of South Carolina $1,016,319 on July 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop multimodal artificial intelligence methods for monitoring and predicting neurocognitive impairment in people with HIV. The project integrates electronic health records, genomic, survey, and imaging data from the National Institutes of Health's All of Us Research Program—a centralized repository with de-identified...
- The National Institute of Mental Health awarded the Regents of the University of Michigan $215,998 on August 19, 2026, under the Mental Health Research Grants program (CFDA 93.242) to deliver the Advancing Research Careers in HIV Program, a two-year research education and mentoring initiative. The program cultivates the next generation of interdisciplinary HIV social and behavioral science researchers by educating and guiding master's-level students in public health, nursing, and social work...
- The National Institute of Mental Health awarded the University of Alabama at Birmingham $409,750 on March 15, 2026, under the Mental Health Research Grants program (CFDA 93.242) to determine the role of localized dopamine signals in learning. The research uses two-photon microscopy and genetically encoded sensors to simultaneously track dopamine release and neuronal activity in real-time as mice perform a neuroprosthetic control task. The work investigates whether dopamine shapes learning at the...
- The National Institute on Drug Abuse awarded the University of Florida $1.76 million on April 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop SYNAPSIS-HIV-CC, a synchronized agentic prescriptive system for optimizing the HIV clinical care continuum. The system combines artificial intelligence agents, large language models, and knowledge graphs to deliver individualized healthcare recommendations across multiple HIV health outcomes: loss of care, viral...
The National Institute of Mental Health awarded the University of Alabama at Birmingham $185,609 on August 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct epidemiologic modeling identifying optimal evidence-based interventions to reduce HIV incidence in Alabama. The award funds mathematical modeling work embedded within a NIAID-funded R01 effectiveness-implementation trial evaluating three combination evidence-based interventions in the southwestern region of Alabama. The recipient will build a compartmental model to simulate the HIV epidemic in Alabama's coastal region and estimate the four-year impact of the three studied interventions on HIV incidence reduction, then assess the impact of statewide scale-up of those interventions. The work incorporates a participatory epidemiologic modeling approach engaging public health leaders and other stakeholders to generate data guiding state HIV intervention planning. Alabama is designated a priority state in the U.S. Ending the HIV Epidemic Initiative; currently only 61 percent of people living with HIV in Alabama have achieved viral suppression compared to the U.S. average of 65 percent and the 2030 national goal of 90 percent. The award is a K01 career development grant, a non-renewable five-year award supporting a junior researcher's independent research career. Performance of work occurs in Birmingham, Alabama from August 1, 2026, through July 31, 2031.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $185.6k | 8/4/26 |