Project Grant R01MH141707
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Trustees of Columbia University in the City of New York a Project Grant totaling $534,191 under the Mental Health Research Grants program (CFDA 93.242) for the period April 1, 2026 through December 31, 2030. The project, titled "Genetic Discovery for Neuropsychiatric Traits in Deep Phenotype Data: Novel Methods and Applications," will develop robust fine-mapping computational tools and...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded $394,200 to the Research Foundation For Mental Hygiene, Inc. (through its New York State Psychiatric Institute division) under the Mental Health Research Grants program (CFDA 93.242) on August 1, 2025, for a five-year project period extending through July 31, 2030. This Project Grant funds a clinical research study examining the role of the anterior hippocampus in major depressive disorder (MDD) pathogenesis....
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Miami a $731,258 Project Grant effective March 1, 2026, through November 30, 2030, under the Mental Health Research Grants program (CFDA 93.242). This research initiative investigates the neural dynamics underlying Major Depressive Disorder (MDD) and Generalized Anxiety Disorder (GAD) by utilizing high-stakes, real-world academic events as naturalistic stimuli. The study will employ...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded Massachusetts General Hospital a Project Grant totaling $183,118 on September 1, 2025, under the Mental Health Research Grants program (CFDA 93.242). Under the direction of Dr. Tubbs, this research initiative will deliver integrated genomic and electronic health record (EHR) analyses designed to advance precision psychiatry by addressing critical gaps in translating genetic findings to clinical practice. The...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded $818,253 to The Regents of the University of California, San Francisco under the Mental Health Research Grants program (CFDA 93.242) beginning July 1, 2025, and extending through April 30, 2030. This Project Grant supports a five-year research investigation examining neuromodulatory system abnormalities in late-life depression (LLD), with specific focus on the associations between structural and functional brain...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Regents of the University of California, San Francisco a Project Grant of $458,177 under the Mental Health Research Grants program (CFDA 93.242) for the period June 9, 2025 through June 8, 2027. The research project, titled "Leveraging Population Level Data to Inform Prevention and Treatment of Adolescent Depression Following Social Adversities," addresses the significant gap between current...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded University of Colorado-Denver $429,000 under the Mental Health Research Grants program (CFDA 93.242) for a two-year exploratory research project spanning June 1, 2025 through May 31, 2027. The project, titled "A Synaptogenic Adhesion Code for Myelin Specificity," investigates the molecular mechanisms underlying myelin formation and white matter abnormalities associated with autism spectrum disorder (ASD)...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded $430,163 to the University of Colorado through the Mental Health Research Grants program (CFDA 93.242) on March 15, 2026, for a two-year project period concluding March 14, 2028. The project deliverable is the validation and clinical translation of Sensor-Based Intervention Monitoring (SBIM), a novel smartphone-based tool designed to reduce the monitoring burden on adolescents undergoing treatment for mood...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Leland Stanford Junior University a Project Grant totaling $192,192.00 (CFDA 93.242, Mental Health Research Grants) beginning April 15, 2026, and concluding March 31, 2031. This award supports the development of an artificial intelligence foundation model designed to advance the understanding and treatment of Major Depressive Disorder (MDD) through functional neuroimaging analysis. The project leverages...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Feinstein Institutes for Medical Research a Project Grant of $519,558 under the Mental Health Research Grants program (CFDA 93.242), effective June 15, 2025 through April 30, 2030. The research project focuses on identifying and validating cerebellar-cortical circuitry biomarkers as predictive indicators of antipsychotic treatment response in first-episode psychosis patients. The primary deliverables...
The National Institute of Mental Health (NIMH) awarded The Regents of the University of Colorado a $730,338 Project Grant effective May 1, 2026, through January 31, 2031, under the Mental Health Research Grants program (CFDA 93.242). The project, titled "Identifying Genetically Distinguishable Subgroups Within Major Depressive Disorder," aims to advance understanding of Major Depressive Disorder (MDD) by identifying distinct genetic subtypes and risk pathways. The research will produce the largest genome-wide association study (GWAS) to date for various MDD subtypes, including sex-stratified, atypical, postpartum, and severe presentations, as well as examinations stratified by age at onset and socioeconomic status. The project will deliver novel methodologies and analytical tools as public research resources, including a Genomic LOSEM (Local-Global Structural Equation Modeling) package for examining non-linear genetic signal changes and Genomic Structural Equation Modeling (Genomic SEM) analyses to disambiguate shared versus subtype-specific genetic signals. These deliverables will characterize genetic risk pathways that are broadly relevant to MDD versus those unique to specific subtypes, advancing the fundamental understanding of MDD's heterogeneous biological underpinnings and supporting development of more targeted treatment approaches.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $730.3k | 5/1/26 |