The National Institute of Mental Health (NIMH) awarded a Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Northwestern University to study the impact of estrogen levels on psychotic-like experiences (PLEs) during the transition from childhood to adolescence. The $225,621 award, with a project period from Aug 2024 to Jul 2026, will leverage the Adolescent Brain Cognitive Development (ABCD) Study dataset to examine how changes in estrogen levels, brain structure and...
The federal Project Grant award R01MH139750 was issued by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The $390,000 award, with a period of performance from April 15, 2025 to February 28, 2030, supports research to examine how hypothalamic prodynorphin neurocircuits integrate defensive behaviors related to anxiety disorders such as post-traumatic stress disorder (PTSD). The research aims to elucidate the neural mechanisms governing...
This Federal Project Grant award R01MH138370, totaling $576,926.00, was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The grant funds a research project at Fordham University to molecularly and cellularly characterize changes in the human anterior hippocampus across the menopausal transition, which is associated with increased risk of major depressive disorder and psychosis in women. The research involves...
The National Institute of Mental Health (NIMH) awarded a Project Grant (CFDA 93.242) totaling $1,022,727.00 to the Rector & Visitors of the University of Virginia (UVA), with a project period from August 1, 2024 to April 30, 2029. The goal of this grant is to study the role of neuroactive steroids, particularly allopregnanolone, and GABA-A receptor plasticity in premenstrual dysphoric disorder (PMDD) and the mechanisms by which low-dose selective serotonin reuptake inhibitors (SSRIs)...
This federal Project Grant award, R01MH134873, was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) to study the molecular and cellular mechanisms by which dopaminergic neurons in the zona incerta (A13 cells) influence extinction learning. The $732,367 award to Children's Hospital Los Angeles will fund a 5-year research project to determine how these dopaminergic neurons contribute to the deficits in extinction learning...
This $2,376,102 Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), is funding research to fine-map and characterize the mechanisms underlying genetic risk factors for post-traumatic stress disorder (PTSD). The primary awardee, The McLean Hospital Corporation, is partnering with sub-awardees at SUNY Downstate Health Sciences University and the University of California, San Diego to: 1) identify causal variants...
This K23 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will provide $180,439 over 5 years to support the Principal Investigator's research into computational neuroscience approaches to understand higher-order threat learning and memory mechanisms in posttraumatic stress disorder (PTSD). The key objectives are to: 1) apply advanced functional MRI analysis techniques like multivariate pattern analysis to...
The National Institute of Mental Health (NIMH) awarded a $200,000 Project Grant (CFDA 93.242 Mental Health Research Grants) to Virginia Polytechnic Institute & State University, known as Virginia Tech, to conduct research on sex differences in the integration of visual social stimulus and emotional auditory stimulus. The project aims to investigate the underlying neural circuit mechanisms that drive synchronized emotional responses, such as fear conditioning, between interacting individuals....
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $178,087 to Michigan State University to conduct research on the regulation of hippocampal neuronal excitability by androgen receptors and its implications for sex differences in major depressive disorder. The research aims to: 1) determine the signaling mechanisms by which androgen receptors regulate ventral hippocampal-nucleus accumbens...
This Project Grant award of $910,241 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program supports research to investigate the relationship between hormonal changes during perimenopause and the emergence or worsening of depressive and anxiety symptoms in women. The award will fund a prospective longitudinal case-control study using a surgical menopause model to measure the associations between hormones, inflammation, and vagal activity...