Project Grant R01MH139142
- The National Institute of Mental Health (NIMH) awarded a $792,441 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to The Mclean Hospital Corporation in Belmont, MA. The grant, awarded on April 15, 2025, will support a research project titled "Tracking the Dynamic Trajectory of Behavioral, Physiological, and Neurobiological Stress Responses in Female Adolescents at High and Low Familial Risk for Depression." The project aims to investigate how parental...
- The National Institute of Mental Health (NIMH) awarded a $147,486 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to the University of Oregon on September 28, 2025. This longitudinal study examines the linkages between neighborhood environment, puberty, sleep quality, and trajectories of depression in adolescent girls. The research aims to 1) identify the direct effects of neighborhood factors on depression, 2) investigate the mediating/moderating role of pubertal...
- This federal Project Grant award of $185,552.00 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to examine the neurocognitive and social factors underlying suicide risk in adolescent girls. The key objectives are to investigate two forms of sustained neurocognitive responsivity to social threat that may disrupt social connectedness and increase suicidal thoughts and behaviors in this population. The research will...
- This federal Project Grant award of $734,220.00 from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), supports research to investigate the impact of early life adversity on positive affect and its neural mechanisms in relation to depression risk. The project aims to: (1) determine if there is a reduction in the behavioral persistence or intensity of positive affect for youth exposed to adversity, (2) examine if individual...
- This Project Grant award of $109,076 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research by Oregon Health & Science University to study the roles of negative life events, emotion regulation, and brain function in the development of internalizing symptoms like depression and anxiety during adolescence. The research aims to elucidate the neurobiological mechanisms underlying the association between negative life...
- This federal Project Grant award of $392,500, provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research to characterize the role of sleep brain dynamics in the emergence of depression among adolescents. The primary awardee, the Research Institute at Nationwide Children's Hospital, will investigate how changes in sleep brain oscillations, such as increased frontal slow wave activity and reduced frontal sleep...
- This $136,113 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research on the neural mechanisms underlying the co-occurrence of depression and anxiety in adolescents. The research aims to use advanced network analysis techniques to identify disturbances in brain networks that are shared by emerging depression and anxiety, providing critical insights into the prevention and treatment of these mental...
- The National Institute of Mental Health (NIMH) awarded a $196,875 Project Grant (CFDA 93.242 - Mental Health Research Grants) to The Ohio State University to conduct research on "Digital Monitoring of Emotion Regulation and Suicidal Ideation Among Individuals at Clinical High Risk for Psychosis". The 2-year study aims to examine emotion regulation as a mechanism for suicidal ideation in individuals at clinical high risk for psychosis, using ecological momentary assessment, wearable...
- This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $2,447,643.00 to the Ohio State University to examine risk factors for depression and suicidal ideation among bisexual adolescents and young adults. Specifically, the research aims to: Identify diverse trajectories of depression and suicidal ideation from adolescence to young adulthood among bisexual individuals; Test identity-related risk factors...
- This federal Project Grant award of $606,029.00 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support research at the University of Massachusetts Medical School (UMass Medical) to investigate the neurocircuitry underlying motivated reward-seeking behavior in response to stress. The key goals of the research are to: 1) Determine if a subpopulation of GABAergic neurons in the medial habenulo-interpeduncular (MHB-IPN) axis...
The National Institutes of Health (NIH) has awarded a 5-year, $200,000 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to The Ohio State University to conduct a longitudinal study on the neural and behavioral mechanisms of stress-reactive rumination and its link to depression risk in adolescent girls. The research aims to: 1) understand how alterations in cognitive-affective brain networks during stress-induced rumination predict future depression trajectories, and 2) examine if naturalistic experiences of stress-reactive rumination in response to daily stressors predict increases in daily depressive symptoms. The study will also assess factors that protect against or exacerbate the relationship between stress-reactive rumination and depression in this population. The research findings have the potential to inform targeted prevention and intervention efforts to address depression risk in adolescent girls.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $200.0k | 9/15/25 |