Project Grant K08MH143093
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Regents of the University of California, San Francisco a Project Grant totaling $117,747 under the Mental Health Research Grants program (CFDA 93.242) to support research on neural computations underlying flexible behavioral control and problem-solving. The award, obligated on May 22, 2026, with a completion date of April 30, 2028, funds basic neuroscience research investigating how the brain implements...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Johns Hopkins University a $608,086 Project Grant effective March 24, 2026, through December 31, 2029, under the Mental Health Research Grants program (CFDA 93.242). This research project investigates the functions of the claustrum in flexible decision-making, with the primary objective of advancing understanding of how the brain generates flexible behavior—a capability disrupted in numerous neuropsychiatric...
- Federal Grant Award Summary This Project Grant, awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), funds basic neuroscience research investigating the cellular and circuit mechanisms underlying value representation and learning in the mouse medial prefrontal cortex (mPFC). The $126,900 award to The Trustees of Columbia University in the City of New York (Health Sciences Division) supports research conducted from April 2, 2026,...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Feinstein Institutes for Medical Research a Project Grant of $519,558 under the Mental Health Research Grants program (CFDA 93.242), effective June 15, 2025 through April 30, 2030. The research project focuses on identifying and validating cerebellar-cortical circuitry biomarkers as predictive indicators of antipsychotic treatment response in first-episode psychosis patients. The primary deliverables...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded a Project Grant of $534,191 to The Trustees of Columbia University in the City of New York, Health Sciences Division, effective April 1, 2026, through December 31, 2030, under the Mental Health Research Grants program (CFDA 93.242). The award supports research on "Genetic Discovery for Neuropsychiatric Traits in Deep Phenotype Data: Novel Methods and Applications." The project addresses...
- Federal Grant Award Summary New York University received a $710,563 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded March 5, 2026, with completion targeted for November 30, 2030. This research initiative will investigate neural circuit mechanisms underlying dynamic learning rates—the brain's ability to adjust the speed of learning based on environmental volatility. The project focuses on identifying how...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a Project Grant of $800,384 to The Regents of the University of California, San Francisco on March 10, 2026, under the Mental Health Research Grants program (CFDA 93.242). This award supports a four-year research project extending through December 31, 2030, focused on elucidating the molecular and functional mechanisms of prefrontal-hippocampal long-range inhibition. The research specifically investigates how...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded $778,548 to the Research Foundation For Mental Hygiene, Inc. (Nathan S Kline Institute Division) on September 19, 2025, under the Mental Health Research Grants program (CFDA 93.242) to support a five-year research project examining sensory contributions to third visual pathway (TVP) dysfunction in schizophrenia. The project, extending through July 31, 2030, investigates the neural mechanisms underlying social...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Johns Hopkins University a Project Grant of $104,349 under the Mental Health Research Grants program (CFDA 93.242) for the period April 1, 2026 through March 31, 2028. The grant funds research on "Attentional Modulation of Neural Activity in Multi-Attribute Decision Making," which investigates how attention influences neural processes during complex decision-making scenarios. The project advances...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded $394,200 to the Research Foundation For Mental Hygiene, Inc. (through its New York State Psychiatric Institute division) under the Mental Health Research Grants program (CFDA 93.242) on August 1, 2025, for a five-year project period extending through July 31, 2030. This Project Grant funds a clinical research study examining the role of the anterior hippocampus in major depressive disorder (MDD) pathogenesis....
The National Institute of Mental Health (NIMH) awarded a $194,400 Project Grant to The Trustees of Columbia University in the City of New York (Health Sciences Division) on May 18, 2026, through the Mental Health Research Grants program (CFDA 93.242). The five-year research project, set to conclude on May 17, 2031, aims to elucidate the neural activity patterns underlying cognitive flexibility—specifically, the brain mechanisms that enable behavioral rule-switching, generalization from past experiences to new situations, and rapid adjustment of learned rules. The research will utilize high-channel count electrophysiological recording methods to simultaneously capture neural activity across multiple brain regions (hippocampus, prefrontal cortex, and motor output regions) in non-human primates performing a custom-developed behavioral task designed to engage each cognitive flexibility function. The primary deliverable of this award is fundamental neuroscience research that will identify specific patterns of neural activity supporting distinct types of cognitive flexibility. These research outputs will contribute to the understanding of cognitive dysfunction mechanisms underlying psychiatric disorders, ultimately supporting the development of more effective treatments targeting impaired cognitive functions. The project also serves as a training vehicle for the principal investigator to acquire advanced technical expertise in multi-region, high-channel count electrophysiological recording methodologies, positioning the researcher to conduct independent, cutting-edge cognition research as an established investigator.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $194.4k | 5/22/26 |