This Project Grant award, funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research on the neural mechanisms underlying socially transmitted aggression in mice. The total funding amount is $185,625.00 and the award period is from January 15, 2025 to December 31, 2026. The primary objective is to study the role of familiarity in socially transmitted aggression, specifically examining the activation and potentiation of...
This federal Project Grant award of $440,000 from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), supports research on sex differences in the integration of visual social stimuli and emotional auditory stimuli. The project, conducted by Virginia Polytechnic Institute & State University (Virginia Tech), aims to investigate the underlying neural circuit mechanisms that drive behavioral synchronization in mice. The research will use...
This federal Project Grant award of $444,125 from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will investigate the role of serotonergic neurons in alterations to adult social behavior following early life adversity. The award, effective May 1, 2025 through April 30, 2027, will use the limited bedding and nesting model of early life adversity in mice to understand links between early experience, the serotonergic system, and social...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), is providing $711,897 to The Leland Stanford Junior University to investigate the role of serotonin in modulating aggressive and prosocial behaviors. The key objectives are to: 1) characterize the temporal dynamics of serotonin's effects on aggression and prosocial behavior; 2) identify the specific subpopulations of neurons in the nucleus accumbens...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), supports research to mechanistically determine the impact of premature birth and serotonin signaling on the development of the prefrontal cortex. The $375,927 award, effective May 1, 2025 through January 31, 2030, will leverage in vivo electrophysiology, optogenetics, chemogenetics, confocal imaging, and behavioral assays to investigate how the timing of...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $133,488 to the University of California, Los Angeles (UCLA) to investigate the effects of early life adversity on the developmental trajectory of avoidance circuitry. The key objectives are to reveal the activity of early life adversity-sensitive neuron ensembles in the basolateral amygdala during threat avoidance behavior, map their brain-wide...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under CFDA Program 93.242 "Mental Health Research Grants", is supporting a 5-year research project titled "A Seasonal Switch: Alternative Neuroendocrine Mechanisms Regulating Aggression". The $727,895 award, granted on May 8, 2025, will enable researchers at Indiana University to investigate how the pineal hormone melatonin orchestrates increased aggressive behavior in males and females...
This Project Grant award of $162,537.67 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support research examining the relationship between child maltreatment, neurodevelopmental trajectories, and adverse mental health outcomes in adolescents. The study will use secondary data analysis of the Adolescent Brain Cognitive Development (ABCD) study to: (1) identify trajectories in adolescent hippocampal development based on...
This federal Project Grant award of $606,029.00 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support research at the University of Massachusetts Medical School (UMass Medical) to investigate the neurocircuitry underlying motivated reward-seeking behavior in response to stress. The key goals of the research are to: 1) Determine if a subpopulation of GABAergic neurons in the medial habenulo-interpeduncular (MHB-IPN) axis...
The National Institute of Mental Health (NIMH) awarded a 3-year, $413,681 Project Grant (CFDA 93.242 - Mental Health Research Grants) to the University of Dayton Research Institute to study the role of phospholamban (PLN), a critical calcium regulatory protein, in the thalamic reticular nucleus (TRN) of the brain. The research aims to decipher the cellular and molecular mechanisms by which PLN regulates the signaling properties of TRN neurons and influences behavioral outcomes like locomotor...