Project Grant R01MH137085
Award Date
7/15/24
Completion Date
4/30/29
Dollars Obligated
$2M
Federal Agency
National Institute of Mental Health
Federal Grant Program
93.242
Assistance Type
Project Grant
Place of Performance
Baltimore, MD 21218, USA
Similar Awards
The National Institute of Mental Health (NIMH) awarded a $633,438 Project Grant (CFDA 93.242 Mental Health Research Grants) to New York University to develop a data-driven framework for real-time neural control and targeted modulation of primate prefrontal cortical circuits. The key objectives are to investigate the principles governing multi-electrode microstimulation patterns and their effects on neural population activity, introduce a novel data-driven algorithm to predict optimal stimulation...
This $1,425,651 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to investigate the neural mechanisms that coordinate learning across distinct cognitive systems. The primary awardee, the University of Maryland, Baltimore, will conduct a multi-year study using advanced behavioral training, electrophysiological recordings, and optogenetic manipulations to identify how the prefrontal cortex...
This federal Project Grant award, valued at $564,556.00 and awarded on February 24, 2025 by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research to determine how cognitive control networks (CCNs) in the brain enable rapid instructed task learning (RITL) abilities. The central hypothesis is that CCNs facilitate RITL through compositional-conjunctive hierarchies, which allow for the rapid transfer of prior learning to novel...
The National Institute of Mental Health (NIMH) awarded a $823,252 Project Grant (CFDA 93.242 - Mental Health Research Grants) to The Trustees of Princeton University on September 18, 2024. The grant will support a 5-year research project titled "CROSS-BRAIN, MULTI-REGION INTERACTIONS IN DECISION FORMATION AND DECISION COMMITMENT" that aims to enhance the understanding of the neural mechanisms underlying decision-making processes. The grant includes a $55,255 sub-award to The Johns...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) is providing $107,948.00 to The Johns Hopkins University to study the computational mechanisms underlying single neuron activity within brain-wide circuits. The research aims to characterize the relationships between synaptic input patterns and action potential generation in cortical neurons, investigate how inputs change when the brain drives specific neuron...
This Project Grant award from the National Institute of Mental Health (NIMH), part of the Mental Health Research Grants federal grant program (CFDA 93.242), provides $267,310 to study the properties and role of dendritic inhibition in the prefrontal cortex of rhesus macaques. The research aims to compare the spatial distribution, kinetics, and synaptic physiology of dendritic inhibition on pyramidal cells in the anterior cingulate cortex (ACC) and lateral prefrontal cortex (LPFC), to elucidate...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $678,430 to The Regents of the University of California, Berkeley (UC Berkeley) from September 2024 to June 2029. The award will fund research to investigate the role of the orbitofrontal cortex (OFC) in inhibiting habitual responses in the striatum to enable goal-directed decision-making. The project will use novel behavioral tasks and advanced...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $608,309 to The Johns Hopkins University to study the role of the claustrum, a subcortical brain region, in flexible decision-making behaviors. The research aims to investigate how claustrum neurons encode decision variables and contribute to persistent activity in the prefrontal cortex, which is critical for cognitive flexibility. The...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), supports research on the neural circuitry underlying model-based decision-making and its relevance to compulsive disorders. The $189,540 grant, awarded on February 1, 2025 to the University of Pittsburgh, aims to determine how model-based control is represented in specific cell types within the prelimbic cortex and dorsomedial striatum, and...
This $252,125 Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), aims to investigate the neural mechanisms underlying context-dependent decision-making in mice. The project will leverage functional magnetic resonance imaging (fMRI) and optogenetics to: Identify brain regions involved in the maintenance of contextual information across the mouse brain, and Determine how activity in these context maintenance areas...