This $770,483 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support research to characterize how biological acute stress response mechanisms influence the severity and trajectory of anhedonia (reduced ability to experience pleasure) in adolescence. The study, conducted by the University of North Carolina at Chapel Hill, will use a multimodal approach including functional MRI, physiological stress reactivity, and clinical/cognitive assessments to identify multisystem stress response biotypes and explore their contributions to anhedonia in 192 adolescents aged 13-15 years. The research aims to develop a novel framework for understanding the complex biological mechanisms governing stress responsivity during adolescence, a critical developmental period, with the goal of informing targeted interventions for adolescents experiencing anhedonia.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $770.5k | 7/12/24 |