Project Grant R01MD021367
- This federal Project Grant award of $649,293 from the National Cancer Institute (CFDA 93.393 Cancer Cause and Prevention Research) aims to study healthcare utilization and outcomes across the cancer care continuum, with a focus on understanding the impact of social risk factors and screening among Latino patients. The 5-year project, awarded to Ochin, Inc., a nonprofit health IT collaborative in Oregon, will leverage a robust electronic health record database spanning over 2 million Latino...
- This $5,041,790 cooperative agreement award from the National Cancer Institute (NCI), under the Cancer Centers Support Grants program (CFDA 93.397), will fund research projects at the University of California, San Francisco (UCSF) to improve cancer health disparities. The key products and services to be delivered include: Three translational cancer health disparities research projects focused on meningioma, prostate cancer, and breast cancer. The projects aim to evaluate the interplay of...
- The University of California, San Francisco (UCSF) was awarded a $6,778,819 Project Grant from the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420). The grant, awarded on April 1, 2024, will fund a 4-year research project to conduct low-pass whole-genome sequencing to improve breast cancer risk assessment in a diverse population. UCSF will serve as the prime awardee, with the University of Chicago receiving a sub-award to contribute...
- This $714,062 Project Grant award from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) is supporting research at the University of California, San Francisco (UCSF) to investigate the biological mechanisms contributing to racial disparities in oral and head and neck cancer outcomes, particularly among Black patients. The key research objectives are to: 1) develop a tailored RNA prognostic model to enhance oral cancer survival predictions in Black populations by identifying...
- The National Cancer Institute (NCI) awarded a $432,304 Project Grant under the Cancer Cause and Prevention Research (CFDA 93.393) program to The Trustees of Columbia University in the City of New York, Health Sciences Division. The grant, awarded on January 3, 2025, supports a 5-year research project focused on "Enhanced Cancer Risk Predictions in Underrepresented Populations through Robust Multi-Source Data Integration." The project aims to develop novel data integration methods to...
- The Regents of the University of California, San Francisco (UCSF) has been awarded a $1,453,500 Project Grant under the Trans-NIH Research Support (CFDA 93.310) program, administered by the National Institutes of Health (NIH). The grant, titled "Simulating Ancestrally Unbiased Tumor Evolution to Interrogate Drug Resistance Among Cancer Patients of Distinct Ancestries," aims to develop an immunocompetent organoid-based tumor graft system, called BRUTE (Barcoded Unsupervised Tumor...
- This $780,113 Project Grant award from the National Human Genome Research Institute (CFDA 93.172 - Human Genome Research) aims to develop methods for quantifying and correcting biases in the genetic study of complex traits. Specifically, the research will: Create a comprehensive simulation framework to model realistic intergenerational dynamics and understand genetic transmission across generations. This will help correct biases in current methodologies used to study genetic architecture....
- The National Institute of General Medical Sciences (NIGMS) awarded a 5-year, $616,786 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to The Regents of the University of California, San Francisco (UCSF) to conduct research aimed at uncovering how evolutionary forces shape patterns of genetic variation and drive phenotypic variation across human populations. The research focuses on three key areas: 1) exploring the effects of recessive deleterious alleles...
- The University of California, San Francisco (UCSF) has been awarded a $726,750 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420). This 3-year federal grant, with a period of performance from June 2024 to June 2027, will support research to elucidate the role of ERα RNA binding activity in breast cancer progression and drug-tolerant persister cells. As a leading academic medical center with extensive experience in federally...
- This Project Grant award from the National Cancer Institute (CFDA 93.393 Cancer Cause and Prevention Research) provides $547,047 to Georgetown University to conduct a clinical trial testing the bundling of multicancer screening and genetic services navigation to improve cancer health equity among Black and Hispanic women. The project aims to address patient- and organization-level barriers that limit cancer screening and genetic testing rates in these populations, which experience...
This federal Project Grant award of $4,307,388.00 from the National Institute on Minority Health and Health Disparities (CFDA 93.307 - Minority Health and Health Disparities Research) will support research by the University of California, San Francisco (UCSF) to identify additional genes in the homologous recombination repair (HRR) pathway associated with breast cancer risk in Hispanic/Latina women. The key objectives are to: 1) Discover additional variants in HRR genes associated with breast cancer in a large dataset of ~12,000 Hispanic/Latina breast cancer cases and ~30,000 controls, using a novel deep-learning approach to classify variants; 2) Determine the functional impact of the identified variants on HRR pathway function; and 3) Assess the association of the identified HRR variants with breast cancer risk, tumor characteristics, and response to PARP inhibitor and platinum-based therapies in Hispanic/Latina women. This research aims to improve genetic risk assessment and management of breast cancer in this underrepresented population.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $4.3m | 8/31/25 |