Project Grant R01LM014401
Award Date
9/4/24
Completion Date
8/31/29
Dollars Obligated
$619K
Federal Agency
National Institute of Environmental Health Sciences
Federal Grant Program
93.879
Assistance Type
Project Grant
Place of Performance
Philadelphia, PA 19104, USA
Similar Awards
The National Institute of Environmental Health Sciences (NIEHS) awarded a $498,042 Project Grant under the Medical Library Assistance (CFDA 93.879) federal grant program to the University of Colorado-Denver. The grant, which runs from September 1, 2024 to August 31, 2027, aims to develop and evaluate multi-modal clinical diagnostic reasoning models for automated diagnosis generation. Key project goals include: Developing a multi-modal generative model that can read structured and unstructured...
This Project Grant awarded by the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) federal grant program provides $249,000.00 in funding from August 1, 2025 to July 31, 2028 to Vanderbilt University Medical Center (VUMC). The grant supports the development and implementation of advanced statistical machine learning methods to shorten the diagnostic and therapeutic "odysseys" faced by patients with rare diseases. Key...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) program will provide $362,813 to The Trustees of the University of Pennsylvania to develop informatics tools to predict virtual spatial transcriptomics data with single-cell resolution. The project aims to integrate histology image data with spatial gene expression data to build predictive models that can generate virtual spatial transcriptomics data at...
This National Science Foundation (NSF) Project Grant award under the Mathematical and Physical Sciences program (CFDA 47.049) provides $250,000 to The Trustees of the University of Pennsylvania to develop advanced statistical methods for integrating and analyzing large-scale data from multiple sources, such as electronic health records and genomics data. The project aims to devise new data-driven algorithms with theoretical optimality guarantees for transfer learning, as well as adversarially...
This $729,821 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) program supports the development of artificial intelligence (AI) and machine learning (ML) methods for real-time monitoring and updating of clinical decision support (CDS) systems. The goal is to reduce health disparities that may arise from the use of CDS tools. The key products of this work include: Fair ML models trained on retrospective...
This federal Project Grant award, funded by the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) program, aims to develop and validate a novel informatics framework to extract computable population, intervention, comparison, and outcome (PICO) elements and summarize them from publications of interventional and observational studies. The total funding amount is $391,388.00, with an award date of September 18, 2024 and an ultimate...
This Project Grant award of $367,876 from the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) program supports research to develop robust Bayesian adaptive designs and methods for multi-arm, multi-dose, multi-stage platform clinical trials. The research aims to address practical challenges in real-world platform trials, such as optimizing sequential monitoring, establishing proof-of-concept and dose selection, managing...
This Project Grant award from the National Human Genome Research Institute (CFDA 93.172 - Human Genome Research) supports research to develop novel computational methods for integrating large-scale genomic datasets to better understand the regulatory networks underlying complex human traits and diseases. The $533,801.84 award, effective September 18, 2024 through June 30, 2027, will enable the awardee, The Trustees of the University of Pennsylvania, to: 1) improve causal structure learning...
This $1,505,109 Project Grant awarded by the National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), aims to identify undiagnosed Alzheimer's disease (AD) in non-Hispanic White, Hispanic/Latino, and non-Hispanic African American populations. The project will leverage electronic health records and genetic data to develop disease trajectory models and polygenic risk scores to detect undiagnosed AD, while addressing the issue of underdiagnosis in underserved...
This Project Grant award from the National Institute of General Medical Sciences (CFDA 93.859 Biomedical Research and Research Training) provides $1,251,000.00 in funding to Pennsylvania State University, doing business as Penn State Milton S. Hershey Medical Center, to develop novel causal machine learning methods that can identify markers and underlying mechanisms contributing to individual treatment response heterogeneity. The project aims to advance the understanding of treatment-disease...