Project Grant R01HL184140
- This Project Grant award of $371,021 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports the development of a continuous respiratory monitoring platform to better classify apnea of prematurity (AOP) in premature newborns. The primary products to be delivered are: 1) a multimodal system and machine learning model to accurately detect and classify the major types of AOP (central, obstructive, and mixed); and 2) an optimized prototype system...
- This is a Project Grant awarded by the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), for the development and implementation of a pediatric AI multi-modal digital stethoscope and respiratory surveillance system in South Africa. The $261,763 award aims to develop and validate an innovative, inexpensive multi-modal digital stethoscope capable of automated lung sound and respiratory rate...
- This National Institutes of Health (NIH) R21/R33 grant award in the amount of $734,360 aims to develop and validate an innovative, inexpensive multi-modal digital stethoscope capable of automated lung sound and respiratory rate analysis, with mobile phone interoperability to an electronic health (eHealth) platform for real-time lower respiratory infection (LRI) and antibiotic surveillance in low- and middle-income countries (LMICs). The grant, awarded under the NIH's Child Health and Human...
- This Project Grant award of $807,067.00 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) will support a study to pioneer the quantitative documentation of human respiratory kinematic profiles. The study aims to address a critical gap in contemporary physiological monitoring - the inability to quantify labored breathing, which contains vital prognostic information not captured by conventional monitoring. Building on a recent innovation called ARK...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $269,922 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Steth X Microsystems Inc. to develop a smart, wearable contact microphone patch for extended and remote monitoring of lung functions. The goal is to create a low-profile, battery-powered wireless device capable of accurately detecting and quantifying adventitious lung sounds as well as breathing abnormalities in patients with respiratory...
- This Project Grant award from the National Heart Lung and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) aims to develop a modern Electrical Impedance Tomography (EIT) device for monitoring children in the Intensive Care Unit (ICU). The $299,900 award to Goodlife Inventors LLC will fund efforts to (1) generate initial designs for an advanced lightweight EIT belt and (2) assess the technical feasibility of a miniaturized, easier to use EIT core device. If...
- This Project Grant award of $497,628.00 from the National Heart Lung and Blood Institute, under the Cardiovascular Diseases Research program (CFDA 93.837), supports research into pulmonary vagal sensory neurons and their role in breathing abnormalities associated with bronchopulmonary dysplasia (BPD) in preterm infants. The research aims to elucidate the dose- and duration-dependent effects of neonatal hyperoxia exposure on breathing control and the functional roles of distinct populations of...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $130,600 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to Marian University Inc. The project, titled "Advancing Wakefulness Screening of Sleep Apnea Disorder Through Breathing Sound Analysis and Hardware Optimization," aims to enhance a wakefulness-based sleep apnea screening tool that utilizes breathing sound analysis to...
- This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $237,827 to Brigham & Women's Hospital Inc. to develop a wearable, non-invasive optical device for continuous blood pressure monitoring in neonates. The device, called CNAP-FlexNIRS, will use near-infrared spectroscopy and photoplethysmography to collect high-resolution pulsatile waveforms and...
- This Project Grant award, valued at $308,712.00 and provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173), aims to develop an automated Auditory Brainstem Response (ABR) testing system incorporating artificial intelligence for telemedicine applications in hearing screening and diagnostic services. The key products and services to be delivered under this grant...
This Project Grant award of $150,000.00, provided by the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310), aims to develop a novel, non-invasive active sound sensing approach with artificial intelligence (AI)-based analysis of breathing sounds integrated on a smart pacifier device for real-time, continuous respiratory monitoring, particularly for neonates. The key products and services to be delivered under this award include: 1) Modeling a new active sound sensing mechanism utilizing breathing sound signal reflections, 2) Designing a miniaturized, low-power smart pacifier interface with active/passive sound sensing capabilities for real-time pulmonary assessment, and 3) Creating a novel AI-guided analysis pipeline for multimodal active sound sensing of respiratory characteristics using deep learning models. Additionally, an open-source breathing sound dataset with active and passive reflections will be created through the study. This research aims to address the significant healthcare burden and challenges associated with respiratory distress syndrome and other pulmonary issues in neonates.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $150.0k | 8/15/25 |