Project Grant R01HL183162
- Federal Grant Award Summary Award Details: The National Heart, Lung, and Blood Institute (NHLBI) awarded a Project Grant of $174,325 to Indiana University Indianapolis under the Cardiovascular Diseases Research program (CFDA 93.837) on August 20, 2025, with a completion date of May 31, 2030. The funding supports the development of an intelligent clinical decision support system designed to improve peripheral arterial disease (PAD) management through advanced artificial intelligence technologies....
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded Indiana University Indianapolis a $1.26 million Project Grant (CFDA 93.837: Cardiovascular Diseases Research) effective August 15, 2025, through May 31, 2029, to conduct research on novel regulatory mechanisms governing neovascularization, cardiomyocyte survival, and endothelial cell-cardiomyocyte crosstalk in myocardial infarction (MI). The research addresses the critical public health burden of...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded Indiana University Indianapolis a Project Grant of $169,444.00 under the Cardiovascular Diseases Research program (CFDA 93.837) beginning September 5, 2025, with completion targeted for August 31, 2030. This award supports the co-development and pilot testing of a stress management intervention designed specifically for Black adults with elevated blood pressure and hypertension. The research addresses...
- Summary of Federal Project Grant Award The National Heart, Lung, and Blood Institute (NHLBI) awarded a Project Grant totaling $414,996 to Indiana University Indianapolis, with an award date of August 15, 2025 and ultimate completion date of May 31, 2030, under the Cardiovascular Diseases Research program (CFDA 93.837). This research project investigates the mechanisms of junctional proteins in post-surgical lymphedema, a chronic condition affecting an estimated 5–10 million Americans. The...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded the University of Florida $756,228 under the Cardiovascular Diseases Research program (CFDA 93.837) on September 4, 2025, to develop an artificial intelligence-enabled predictive model for chronic limb-threatening ischemia (CLTI) revascularization outcomes. The research addresses a critical gap in current predictive models, which demonstrate limited prognostic accuracy (area under the receiver operating...
- Federal Project Grant Award Summary Purdue University received a $150,011 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded September 1, 2025, with a completion date of July 31, 2029. The project develops an artificial intelligence (AI)-guided intraoral multimodal active sound sensing system integrated into a smart pacifier device for real-time, continuous respiratory monitoring in neonates. The...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded $156,899 to the Trustees of Indiana University (Indiana University Indianapolis) under the Cardiovascular Diseases Research program (CFDA 93.837) on July 20, 2025, with an ultimate completion date of June 30, 2030. This K01 career development award supports research to identify distinct clinical phenotypes in pediatric status asthmaticus (severe acute asthma exacerbations) and determine differential...
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded the University of Illinois a Project Grant totaling $109,076 (awarded September 30, 2025, with completion scheduled for September 29, 2030) under the Cardiovascular Diseases Research program (CFDA 93.837). The University of Illinois will develop an individualized prediction methodology for heart failure progression using digital twin technology and explainable machine learning. Leveraging data...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded a $249,000 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Indiana University Indianapolis, effective August 1, 2025, through June 30, 2028. This award supports Dr. James's career development and research training initiative focused on investigating aminopeptidase N (APN) driven signaling and mitochondrial dysfunction in pulmonary hypertension (PH). The primary deliverables...
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded the University of North Carolina at Chapel Hill a $699,296 Project Grant (CFDA 93.837 – Cardiovascular Diseases Research) effective August 15, 2025 through May 31, 2029 to investigate optimal treatment algorithms and tailor therapeutic strategies for patients with chronic limb-threatening ischemia (CLTI). The research leverages data from the NHLBI-sponsored Best-CLI randomized controlled trial...
The National Heart, Lung, and Blood Institute (NHLBI) awarded Indiana University a Project Grant totaling $742,465 on June 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop and validate a behavioral large language model (LLM) for identifying guideline-directed medical treatment (GDMT) prescriptions in peripheral artery disease-related claudication. The primary deliverable is a validated behavioral LLM that extracts and quantifies unstructured clinical notes to identify prescriptions of behavioral GDMTs, addressing a critical gap in clinical practice where evidence-based first-line treatments remain underprescribed despite proven efficacy in preventing major adverse vascular events. This research will leverage generative artificial intelligence and digital health advancements to convert qualitative electronic health record data into structured, analyzable data. The secondary objective and deliverable involves characterizing patient-level factors influencing GDMT prescription and treatment outcomes in the approximately 10 million individuals with claudication. The award, which concludes on March 31, 2031, will be performed at Indiana University's Bloomington, Indiana campus. By producing quantified behavioral treatment data and understanding prescription variation patterns, this project aims to improve clinical implementation of guideline-directed treatments and enhance outcomes in peripheral artery disease management across the broader patient population.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $742.5k | 5/26/26 |