This federal Project Grant award of $448,968.00, provided by the National Heart Lung and Blood Institute (NHLBI) under the Cardiovascular Diseases Research Program (CFDA 93.837), supports research to investigate the neurobiological mechanisms linking chronic stress to sex-specific cardiovascular outcomes. The principal investigator at Colorado State University will utilize viral-mediated techniques to study synaptic plasticity within the infralimbic prefrontal cortex-posterior hypothalamus...
This federal Project Grant award of $2,428,701 from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports a comprehensive, prospective evaluation of 1,000 pregnant individuals with cardiovascular disease (CVD) across 33 partner sites. The study aims to: Identify patient characteristics associated with adverse pregnancy outcomes, maternal adverse cardiac events, neonatal adverse clinical events, and quality of life, with a focus on racial...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $103,948 to the University of Denver to conduct research examining associations between discrimination experienced during pregnancy and later maternal cardiovascular disease (CVD) risk factors. The 2-year project aims to: 1) test if greater discrimination during pregnancy is linked to greater overall maternal CVD risk at 3-4 years...
This federal Project Grant award of $106,636 from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), aims to enable Dr. Ida Fonkoue to launch an independent research career. The award will support longitudinal research on the impact of Post-Traumatic Stress Disorder (PTSD) on vascular and autonomic function in premenopausal women. The overarching goals are to: 1) expand on Dr. Fonkoue's current K01 research; 2) provide...
This federal Project Grant award of $418,178 from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to provide mechanistic insights into the neurobiological mechanisms by which maternal sensitivity is compromised by postpartum depression. Specifically, the University of Massachusetts (UMass), through its Office of Grant & Contract Administration, will use intersectional viral...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $242,310 to The Medical University of South Carolina to study the mechanisms connecting post-traumatic stress disorder (PTSD) and cardiovascular disease (CVD). The central hypothesis is that PTSD stimulates chronic inflammation, leading to recruitment of monocyte-derived macrophages to the heart, which in turn increases cardiac...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $647,174 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to The Miriam Hospital Lifespan Division to investigate the long-term effects of prenatal mindfulness training on maternal and infant cardiovascular disease risk. This 5-year research project will follow 130 participants and their infants enrolled in a parent RCT study to measure the impact of prenatal mindfulness training on postpartum...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $869,696 to Vanderbilt University Medical Center (VUMC) to conduct a large prospective study investigating the hypothesis that preeclampsia leads to persistent cardiovascular changes that mirror early heart failure with preserved ejection fraction (HFPEF). The key objectives are to: 1) measure the relationship between...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $1,438,522 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Rutgers, The State University of New Jersey, to investigate the biopsychological processes through which daily psychosocial stress affects cardiometabolic health among 300 older foreign-born Chinese Americans. The study aims to determine the mediation effects of daily negative emotion, cortisol secretion, and sleep quality on the...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $696,470 to the University of Denver to conduct research on the impact of prenatal maternal sleep on offspring cardiovascular disease risk. The 5-year project will objectively measure maternal sleep patterns across pregnancy and evaluate how they relate to maternal biological processes (stress, inflammation), infant growth and adiposity,...