Project Grant K01HL177168
- This federal Project Grant award, totaling $1,621,874.00, was provided by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837) with an award date of Sep 23, 2025 and an ultimate completion date of Jun 30, 2027. The award was granted to Brigham & Women's Hospital Inc., a subsidiary of the larger Partners Healthcare System (now Mass General Brigham), to conduct research on the role of ambient lighting in circadian misalignment and its...
- This $254,250 project grant from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) aims to advance understanding of the relationship between neighborhood factors and sleep health disparities among first and second grade students, primarily Black children, living in urban New York City neighborhoods. The study will merge a comprehensive public dataset on neighborhood characteristics (Child Opportunity Index 3.0) with a longitudinal dataset from a...
- This federal Project Grant award for $696,470, provided by the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research), aims to investigate the relationship between prenatal maternal sleep and cardiovascular disease risk in offspring. The University of Denver is the primary awardee, and they have sub-awards with Northwestern University and the University of Colorado, Anschutz Medical Center. The key objectives are to: 1) examine how prenatal maternal sleep...
- This Project Grant award for $730,993.00 from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research to investigate the mechanisms by which internal circadian misalignment contributes to the cardiometabolic risk associated with sleep loss. The project aims to determine if preventing light exposure and food intake during the circadian biological night can mitigate the adverse cardiometabolic effects of insufficient sleep. Researchers at...
- This federal Project Grant award, valued at $678,710 and awarded on June 15, 2025, was provided by the National Heart, Lung, and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837). The award supports the development and validation of a novel multi-sensor machine learning approach to precision sleep tracking for nightshift workers. The project aims to leverage wearable devices, environmental sensors, and machine learning algorithms to accurately detect sleep patterns...
- This Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $818,279 to Brigham & Women's Hospital, a subsidiary of Partners Healthcare System, to conduct research on improving the subtyping and characterization of obstructive sleep apnea (OSA). The project will leverage data from existing research cohorts and a clinical biobank to quantify the reproducibility of OSA severity markers and derive physiologically...
- This federal Project Grant award, provided by the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research), supports a comprehensive sleep neuroimaging study to investigate the role of local sleep disturbance in obesity risk. The $568,125 award to Brigham Young University, with a period of performance from September 2025 to August 2028, will utilize advanced functional neuroimaging and polysomnographic methods to elucidate the underlying mechanisms linking poor...
- This $691,124.00 project grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports research on the relationship between circadian disruption and cardiometabolic risk during the transition from adolescence to young adulthood. The project aims to test the hypothesis that persistent circadian disruption, including misaligned sleep, eating, and activity timing, will be related to the development of cardiometabolic risk through epigenetic...
- This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $594,547 to Harvard Medical School to conduct research on the regulation of arousal and sleep quality. The project aims to characterize a gut-to-brain signaling pathway that uses information about ingested nutrients to control arousal levels and sleep depth, without affecting overall sleep duration. The research will investigate...
- This federal Project Grant award for $743,388, awarded by the National Heart, Lung, and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837), supports research on the mechanisms by which sleep loss and circadian misalignment contribute to insulin resistance and the development of Type 2 diabetes mellitus. The award will fund two randomized controlled trials with 48 adult participants to characterize the role of cortisol rhythms and downstream metabolomic and endocrine...
This federal Project Grant award, provided by the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research), will fund research to investigate place-based factors contributing to sleep health disparities in the United States. The $177,385 award to Brigham & Women's Hospital Inc., a subsidiary of Partners Healthcare System, will: 1) Estimate sleep health measures and environmental circadian misalignment across different populations and geographies; 2) Examine the association between individual-level and place-based factors (e.g. noise) with sleep health disparities; and 3) Test whether place-based factors mediate observed sleep health disparities. This research aims to inform targeted interventions to improve sleep health and related cardiovascular outcomes, particularly among health disparity populations. The project will run from September 2025 to August 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $177.4k | 9/18/25 |