This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $893,525 to The Johns Hopkins University to implement and evaluate a multi-component intervention to protect lung health in Nepal. The 5-year project aims to reduce environmental risk factors like tobacco smoking and air pollution, as well as infectious risks, through community health worker-delivered education, household...
The National Institute of Environmental Health Sciences (NIEHS) awarded a $272,910 Project Grant (CFDA 93.113 Environmental Health) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to optimize and evaluate the use of portable air cleaners (PACs) to reduce particulate matter (PM) exposure in low and middle-income households in Uganda. The project aims to: 1) identify environmental factors that maximize PM reduction with PAC use, 2) design and test an...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $705,279 Project Grant (CFDA 93.837 - Cardiovascular Diseases Research) to Trustees of Boston University, doing business as Boston University Medical Campus, to investigate the mechanisms by which environmental pollutants impact the cardiovascular system. The 4-year project, starting January 1, 2025, will use a multidisciplinary approach including physiological studies, cellular imaging, RNA-sequencing, and mouse models to...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $1,377,026.00 to the Icahn School of Medicine at Mount Sinai to conduct a randomized controlled trial on prenatal and infant household air pollution exposure, the human microbiome and virome, and childhood lung function in Ghana. The research aims to assess how randomized early life air pollution exposure programs subsequent...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research federal grant program (CFDA 93.837), will fund a study on the early life predictors of airway-to-lung mismatch, a condition known as dysanapsis. The primary awardee, The Trustees of Columbia University in the City of New York, will receive $753,018 to leverage longitudinal data from 8 diverse birth cohorts to examine the relationship between early-life exposures, such...
This $149,857 Project Grant, awarded on July 7, 2025 by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program, supports research to investigate the role of inhaled particulate matter (PM) in exacerbating pulmonary vascular remodeling associated with pulmonary hypertension (PH). The research aims to define population-level associations between aryl hydrocarbon receptor (AhR) agonism, plasma metabolites, and PH severity; determine if...
This federal Project Grant award, valued at $154,861 and provided by the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research), aims to advance the integration of social and medical care to promote health equity among children with asthma. The key products and services to be delivered under this grant include: Developing a population-based machine learning model to predict risk of asthma-related hospitalization among children in Washington, D.C. using social...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) Federal Grant Program provides $676,077 to Colorado State University (CSU) to study the impacts of fine particulate matter (PM2.5) air pollution on cardiovascular and respiratory health outcomes. The key products and services being delivered under this award include: Deploying a national network to measure the oxidative potential of PM2.5 samples, which...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $762,867 to The Johns Hopkins University to conduct research on the role of the protein cofilin-1 in maintaining mitochondrial function and airway epithelial health. The research aims to 1) determine how the loss of cofilin-1 impacts mitochondrial dynamics, 2) assess the effects of cofilin-1 loss on mitophagy and mitochondrial...
This $565,250 federal Project Grant award was provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The grant supports a 5-year longitudinal study led by Duke University to characterize the effects of host-microbiome interactions on pulmonary function in a cohort of 500 adults with and without HIV in Botswana. The study will utilize advanced multi-omics techniques, including shotgun metagenomic sequencing, host...