This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) will provide $631,630 to The Johns Hopkins University to conduct a long-term study on the health impacts of a household air pollution intervention in Peru. The primary objectives are to determine the effects of an 18-month liquefied petroleum gas (LPG) stove and fuel intervention on children's lung function, cardiovascular risk profile, and...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $1,377,026 to support the "Prenatal and Infant Household Air Pollution Exposure, the Human Microbiome and Virome, and Childhood Lung Function: The GRAPHS Randomized Controlled Trial" project. The goal of this research is to assess how randomized early life exposure to household air pollution (HAP) impacts the development...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $657,262 Project Grant (CFDA 93.837 - Cardiovascular Diseases Research) to The Johns Hopkins University to conduct implementation research on scaling up community-based interventions for managing non-communicable diseases (NCDs) in Pokhara, Nepal. The overarching goal is to develop an intervention package called SCALE-NCD that leverages community health workers to concurrently address hypertension, diabetes, and smoking in an...
This $186,075 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program supports research at the University of Nebraska Medical Center (UNMC) to investigate the role of the ACOD1-itaconate immunometabolic pathway in regulating lung monocyte/macrophage inflammatory processes induced by environmental exposures.
The key objectives are to determine the functional effects of modulating the...
This federal Project Grant award of $343,146 from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, will support research on the mortality risk associated with air pollution exposure among veterans with chronic respiratory diseases (CRD) such as asthma and COPD.
The research aims to: 1) estimate the mortality risk in CRD populations attributed to daily fine particulate matter (PM2.5) and ozone exposure, and identify...
This $213,284 federal Project Grant award was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program to the University of North Carolina at Chapel Hill (UNC-CH). The grant aims to investigate the mechanisms by which wildfire smoke exposure, particularly in individuals with asthma, impacts human health through the role of extracellular vesicles and the hypoxia-inducible factor 1 (HIF-1) pathway. The research will involve...
This federal Project Grant award in the amount of $1,170,080.00, provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program, supports applied implementation research for clean cooking interventions in Cambodia. The goal is to design and demonstrate an effective, scalable strategy to achieve equitable access to and sustained use of induction-based clean cooking solutions among low-income households.
The award will fund...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program aims to optimize air purification strategies to reduce household particulate matter (PM2.5) exposure in Uganda. The total funding amount is $272,910 over the project period from July 2024 to June 2026.
The key research objectives are to: 1) identify environmental factors that maximize PM reduction with portable air cleaners (PACs) in...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $144,085 to Lehigh University to develop a syndromic surveillance system for chronic respiratory syndrome in Pennsylvania. The key products and services to be delivered include:
Instituting an early-warning system to enable Pennsylvania citizens to visualize risks for chronic respiratory conditions like asthma and COPD, as well...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program provides $671,165 in funding to the University of North Carolina at Chapel Hill (UNC-CH) to conduct research on the genetic mechanisms underlying respiratory responses to ozone (O3) exposure. The key objectives are to:
Identify genes and pathways in alveolar macrophages that determine adaptation or failure to adapt to repeated O3...