Project Grant R01HL177203
- This federal Project Grant award of $639,474, provided by the National Heart, Lung, and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837), supports a study to investigate the impact of maternal mental health interventions on child respiratory health. The study aims to leverage an ongoing birth cohort in rural Pakistan to generate evidence on how childhood adversity, such as poverty and maternal depression, affects respiratory function and symptoms in early...
- The National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, awarded a $667,776 Project Grant under the Cardiovascular Diseases Research (CFDA 93.837) program to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH). The 5-year grant, with a start date of June 15, 2025 and an end date of April 30, 2030, aims to generate clinical evidence on the use of antenatal late preterm steroids (ALPS) to reduce preventable neonatal...
- This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $166,752 to Boston Medical Center Corporation to develop models of placenta-driven developmental lung injury in human preeclampsia. The 5-year project aims to characterize the influence of human preeclampsia on fetal lung development. Specifically, the research will: 1) Identify preeclampsia-specific placental proteins in the fetal circulation that...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $106,391 to the University of Colorado-Denver to investigate the role of developmental dysanapsis in lung development over the lifespan in an experimental bronchopulmonary dysplasia (BPD) model. The research aims to determine whether intra-amniotic endotoxin causes persistent dysanaptic growth of the airways, distal parenchyma, and vasculature in BPD, and...
- This is a Project Grant awarded by the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), for the development and implementation of a pediatric AI multi-modal digital stethoscope and respiratory surveillance system in South Africa. The $261,763 award aims to develop and validate an innovative, inexpensive multi-modal digital stethoscope capable of automated lung sound and respiratory rate...
- This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $166,395 to Columbia University to conduct a 5-year research project on the impact of hyperoxia (excess oxygen) on the function of respiratory progenitor cells in neonates. The project aims to develop a better understanding of the mechanisms by which post-natal lung development occurs in the face of injurious agents like oxygen...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA Program 93.837 Cardiovascular Diseases Research) provides $730,070 to the University of Arizona to develop and test a novel class of hybrid polyplex nanoparticles (P22-F1 PBAE/PEI/PEG) that can specifically target and deliver DNA plasmids to lung capillary endothelial cells. The goal is to stimulate lung regeneration and decrease pulmonary hypertension in mouse and rat models of bronchopulmonary dysplasia, a severe...
- This $186,896 Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) will fund a study by the Regents of the University of California, San Francisco (UCSF) to examine the impact of adverse childhood experiences (ACEs) screening and behavioral-social support on asthma and chronic obstructive pulmonary disease (COPD) health outcomes. The study aims to leverage data from LADHS' implementation of ACEs screening to 1) analyze the...
- This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $586,021 to The Medical College of Wisconsin, Inc. to establish patient-reported outcome measures that refine neonatal risk stratification and identify barriers to post-discharge specialty care for preterm infants with bronchopulmonary dysplasia (BPD). The goal is to identify hospital-to-home transition strategies that reduce post-prematurity respiratory...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $771,750 to the Albert Einstein College of Medicine to conduct a cluster randomized controlled trial called "PRAGMATIC-S". The project aims to create an innovative interface between primary care and school-based programs to optimize the delivery of guideline-based asthma care to urban children with persistent or uncontrolled asthma. The award period runs...
The Project Grant award, titled "EFFICACY OF ANTENATAL CORTICOSTEROIDS ON THE LUNG DEVELOPMENT OF PREMATURE CHILDREN IN BANGLADESH - THE BILDING-ACTION COHORT", was provided by the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to The Johns Hopkins University for $517,972.00. The project aims to leverage two World Health Organization randomized trials in Bangladesh to assess whether antenatal corticosteroids (ACS), versus placebo, improves lung growth, development, and reduces lower respiratory infections among premature children born before 34 weeks and between 34-36 weeks and 6 days. The study will utilize innovative lung function testing and a digital stethoscope with automated analytics to evaluate ACS efficacy over the 6-8 year period following birth. This project seeks to generate new insights into the impact of ACS on respiratory health outcomes for premature infants in low- and middle-income countries where preterm birth complications are a leading cause of child mortality.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $55.1k | 9/24/25 | ||
| Not listed | $183.1k | 9/24/25 | ||
| Not listed | $279.8k | 9/23/25 |