Project Grant R01HL180944
Award Date 9/15/25
Completion Date 6/30/29
Dollars Obligated $639K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Chapel Hill, NC 27599, USA
Similar Awards
- This federal Project Grant award of $727,080 from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research to investigate the neurogenic mechanisms underlying psychosocial stress-induced cardiovascular disease and postpartum depression. The primary research objective is to delineate how stress-evoked mitochondrial dysfunction in the medial prefrontal cortex contributes to postpartum cardiovascular and behavioral changes. The 4-year project,...
- This Project Grant award of $807,067.00 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) will support a study to pioneer the quantitative documentation of human respiratory kinematic profiles. The study aims to address a critical gap in contemporary physiological monitoring - the inability to quantify labored breathing, which contains vital prognostic information not captured by conventional monitoring. Building on a recent innovation called ARK...
- This $186,896 Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) will fund a study by the Regents of the University of California, San Francisco (UCSF) to examine the impact of adverse childhood experiences (ACEs) screening and behavioral-social support on asthma and chronic obstructive pulmonary disease (COPD) health outcomes. The study aims to leverage data from LADHS' implementation of ACEs screening to 1) analyze the...
- This $1,831,848 Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research to investigate how early-life disruptions to gut microbiota colonization can remodel the development of lung immune and epithelial cells, contributing to chronic respiratory diseases. The research aims to identify the critical window and key microbial taxa required for establishing long-term lung homeostasis. Preliminary data indicates that...
- This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $586,021 to The Medical College of Wisconsin, Inc. to establish patient-reported outcome measures that refine neonatal risk stratification and identify barriers to post-discharge specialty care for preterm infants with bronchopulmonary dysplasia (BPD). The goal is to identify hospital-to-home transition strategies that reduce post-prematurity respiratory...
- This federal Project Grant award of $805,921 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to integrate multi-trait, multi-ancestry, and multi-omic data from massive global biobanks to decipher the genetic mechanisms underlying respiratory diseases like chronic obstructive pulmonary disease (COPD) and asthma. The award, with a performance period from September 2025 to June 2030, will leverage data from over 2 million participants,...
- This $680,562 federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research investigating the long-term lung epithelial alterations resulting from early-life respiratory syncytial virus (RSV) infection. The research aims to determine the mechanisms by which early-life RSV infection predisposes individuals to developing asthma later in life, focusing on the role of innate cytokines like IL-1β and IL-33 in driving...
- This federal Project Grant award for $696,470, provided by the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research), aims to investigate the relationship between prenatal maternal sleep and cardiovascular disease risk in offspring. The University of Denver is the primary awardee, and they have sub-awards with Northwestern University and the University of Colorado, Anschutz Medical Center. The key objectives are to: 1) examine how prenatal maternal sleep...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $106,391 to the University of Colorado-Denver to investigate the role of developmental dysanapsis in lung development over the lifespan in an experimental bronchopulmonary dysplasia (BPD) model. The research aims to determine whether intra-amniotic endotoxin causes persistent dysanaptic growth of the airways, distal parenchyma, and vasculature in BPD, and...
- This Project Grant award, provided by the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research), aims to support a mentored implementation science research program focused on improving asthma care and outcomes for children from marginalized communities. The $120,363 award, effective August 18, 2025, will fund Dr. Michelle Eakin's efforts to expand her mentoring program in patient-oriented implementation science. The project will leverage ongoing data collection...