Project Grant R01HL175626
- This federal Project Grant award of $234,000.00 was provided by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837) to test the hypothesis that darker skin pigmentation is associated with increased bias in pulse oximeter performance. The project aims to prospectively determine the effects of directly measured skin pigmentation on pulse oximeter accuracy, as current studies rely on subjective race and ethnicity measures which are poor...
- The National Heart Lung and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), awarded a $707,410 project grant to Duke University to address inequities in pulse oximetry related to skin tone. The "Overcoming Inequities in Pulse Oximetry Through Clinical Informatics (OPTIC)" project aims to develop machine learning models to predict which patients are at high risk for "hidden hypoxemia" and identify those who would benefit from...
- This federal Project Grant award of $134,537 from the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837) aims to develop a novel, noninvasive and auto-calibrated pulse-oximetry method that can more accurately and unbiasedly determine a person's arterial oxygen saturation compared to conventional pulse-oximetry. The key products and services to be delivered through this 5-year project include: 1) Theoretical development of the...
- This Project Grant award of $807,067.00 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) will support a study to pioneer the quantitative documentation of human respiratory kinematic profiles. The study aims to address a critical gap in contemporary physiological monitoring - the inability to quantify labored breathing, which contains vital prognostic information not captured by conventional monitoring. Building on a recent innovation called ARK...
- This Project Grant award from the National Heart Lung and Blood Institute, under the Cardiovascular Diseases Research federal grant program (CFDA 93.837), provides $186,408 to the University of Washington to develop robust models that identify patients at high risk for persistent hypoxemic respiratory failure (HRF). The goal is to improve the ability to distinguish patients with persistent HRF early, which is critical for enrolling the highest-risk patients in clinical trials for new HRF...
- This federal Project Grant award of $110,635.00 from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) aims to characterize how red blood cell aggregation and membrane deformability affect endothelial cell injury and microvascular thrombosis in sepsis patients. The project will use microfluidics assays to analyze patient blood samples and apply machine learning to determine the impact of rheology on clinical outcomes. The research will also assess the...
- This federal Project Grant award from the National Heart Lung and Blood Institute under CFDA Program 93.837 - Cardiovascular Diseases Research provides $306,872 to Airalux Medical, Inc. to develop a digital incentive spirometry device. The goal is to improve patient adherence and clinical workflows for preventing post-surgical lung complications, which occur in 1 in 20 patients undergoing an overnight hospital stay. The device uses sensors and software to automatically track patient usage and...
- This Project Grant award of $371,021 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports the development of a continuous respiratory monitoring platform to better classify apnea of prematurity (AOP) in premature newborns. The primary products to be delivered are: 1) a multimodal system and machine learning model to accurately detect and classify the major types of AOP (central, obstructive, and mixed); and 2) an optimized prototype system...
- This federal Project Grant award of $649,678, provided by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837), supports the development of a high-speed, wearable speckle contrast optical spectroscopy (SCOS) system for cuffless blood pressure monitoring. The project aims to convert the existing benchtop SCOS technology into a wearable device capable of multi-hour ambulatory monitoring, and to test the technique in a wider range of subjects,...
- This federal Project Grant award, valued at $162,703.00 and granted by the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research), aims to determine whether streamlined, standardized blood pressure (BP) measurement protocols can be implemented in primary care settings. The project builds on the Alabama Cardiovascular Cooperative's Heart Health Improvement Project and seeks to improve the accuracy and efficiency of BP measurements to inform treatment decisions...
This Project Grant award from the National Heart Lung and Blood Institute, under the Cardiovascular Diseases Research federal grant program (CFDA 93.837), aims to develop and validate correction algorithms to improve the accuracy of pulse oximeters and temporal thermometers for patients with acute respiratory failure. The $584,575 award to Emory University will quantify the role of melanin in infrared device errors, and use structural equation modeling to create innovative correction algorithms accounting for factors like melanin, bilirubin, dyshemoglobins, age, sex, perfusion, and comorbidities. The goal is to address racial disparities in the accuracy of these essential medical devices, which is critical for the over 1 million adults admitted annually to U.S. intensive care units for acute respiratory failure. The award has an ultimate completion date of May 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $584.6k | 9/8/25 |