Project Grant R03HL178873
- The National Heart Lung and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), awarded a $707,410 project grant to Duke University to address inequities in pulse oximetry related to skin tone. The "Overcoming Inequities in Pulse Oximetry Through Clinical Informatics (OPTIC)" project aims to develop machine learning models to predict which patients are at high risk for "hidden hypoxemia" and identify those who would benefit from...
- This Project Grant award from the National Heart Lung and Blood Institute, under the Cardiovascular Diseases Research federal grant program (CFDA 93.837), aims to develop and validate correction algorithms to improve the accuracy of pulse oximeters and temporal thermometers for patients with acute respiratory failure. The $584,575 award to Emory University will quantify the role of melanin in infrared device errors, and use structural equation modeling to create innovative correction...
- This federal Project Grant award of $134,537 from the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837) aims to develop a novel, noninvasive and auto-calibrated pulse-oximetry method that can more accurately and unbiasedly determine a person's arterial oxygen saturation compared to conventional pulse-oximetry. The key products and services to be delivered through this 5-year project include: 1) Theoretical development of the...
- The federal Project Grant award of $731,827 from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) is supporting research conducted by the J. David Gladstone Institutes in San Francisco, CA to investigate the mechanisms of oxygen toxicity. The key objectives include: 1) testing whether specific molecular pathways (diphthamide synthesis, de novo purine synthesis, and mitochondrial electron transport chain) are necessary and sufficient for impaired cell...
- This Project Grant award of $807,067.00 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) will support a study to pioneer the quantitative documentation of human respiratory kinematic profiles. The study aims to address a critical gap in contemporary physiological monitoring - the inability to quantify labored breathing, which contains vital prognostic information not captured by conventional monitoring. Building on a recent innovation called ARK...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $460,920 to Auburn University to conduct research on the relationship between discrimination and sleep problems in Black Americans. The study will use ecological momentary assessments and actigraphy to investigate how discrimination triggers emotion invalidation, termed "social pain minimization," which negatively impacts sleep. The research will also...
- This federal Project Grant award of $649,678, provided by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837), supports the development of a high-speed, wearable speckle contrast optical spectroscopy (SCOS) system for cuffless blood pressure monitoring. The project aims to convert the existing benchtop SCOS technology into a wearable device capable of multi-hour ambulatory monitoring, and to test the technique in a wider range of subjects,...
- The University of Pittsburgh was awarded a $300,000 federal Project Grant from the National Heart Lung and Blood Institute's Cardiovascular Diseases Research program (CFDA 93.837) to conduct research on "REAL-TIME EVALUATION OF ACUTE MYOCARDIAL INFARCTION WITH MULTI-LEAD ECG MONITORING FROM WEARABLE PPG MEASUREMENTS". The grant, awarded on September 15, 2025, will support the university's research efforts to advance the scientific understanding of cardiovascular health through the...
- This Project Grant award, valued at $498,991.40, was provided by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837) to the University of Arkansas, Fayetteville. The goal is to engineer microphysiological systems with tight oxygen control to investigate the molecular pathways activated in oxygen gradients and the resulting effects on cardiomyocyte function, in order to obtain a comprehensive understanding of the cardiac response to hypoxic...
- This $116,625 federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) will characterize clinically relevant phenotypes related to osteoporosis and sarcopenia in chronic obstructive pulmonary disease (COPD). The project will develop automated methods to derive static metrics of spine, vertebrae, and pectoral muscles, as well as dynamic metrics of lung diaphragmatic surface deformation, from chest CT scans. It will then use...
This federal Project Grant award of $234,000.00 was provided by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837) to test the hypothesis that darker skin pigmentation is associated with increased bias in pulse oximeter performance. The project aims to prospectively determine the effects of directly measured skin pigmentation on pulse oximeter accuracy, as current studies rely on subjective race and ethnicity measures which are poor proxies for skin pigmentation. The University of Colorado-Denver, the awardee, will conduct research to better understand the relationship between skin pigmentation and pulse oximetry bias, with the goal of mitigating delays in care and unrecognized eligibility for treatments among patients with darker skin tones. The award period runs from September 1, 2025 through August 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $234.0k | 8/22/25 |