Project Grant R43HL180242
- This $471,544 Project Grant awarded by the National Institute of Environmental Health Sciences (CFDA 93.879 - Medical Library Assistance) supports the development of novel technologies by Spiromatics, Inc. for the detection and monitoring of obstructive lung diseases such as COPD and asthma. Spiromatics is creating a portable, handheld spirometer with audiovisual coaching capabilities to enhance the assessment and diagnosis of abnormal lung function. The innovative solutions aim to detect an...
- This Project Grant award of $807,067.00 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) will support a study to pioneer the quantitative documentation of human respiratory kinematic profiles. The study aims to address a critical gap in contemporary physiological monitoring - the inability to quantify labored breathing, which contains vital prognostic information not captured by conventional monitoring. Building on a recent innovation called ARK...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $269,922 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Steth X Microsystems Inc. to develop a smart, wearable contact microphone patch for extended and remote monitoring of lung functions. The goal is to create a low-profile, battery-powered wireless device capable of accurately detecting and quantifying adventitious lung sounds as well as breathing abnormalities in patients with respiratory...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $322,277 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Linshom Medical, Inc. in Baltimore, Maryland. The grant will fund clinical development activities focused on demonstrating the health economic value of Linshom's Continuous Predictive Respiratory Monitoring (CPRM) system. The CPRM system aims to reduce morbidity and mortality due to respiratory compromise while lowering healthcare costs...
- This federal Project Grant award, provided by the National Heart Lung and Blood Institute under CFDA program 93.837 Cardiovascular Diseases Research, aims to develop new flexible 3D-printed airway splint designs and computational models to predict airway growth and device damage for the treatment of tracheobronchomalacia in children. The $709,172 award to Georgia Tech Research Corporation will fund pre-clinical and clinical studies over a 5-year period from September 2025 to June 2030. The key...
- This Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $306,530.00 to Spinhance LLC to build, qualify, and evaluate the clinical feasibility of a novel cardiopulmonary imaging device. The device is designed for continuous administration of the magnetic resonance imaging (MRI) contrast agent hyperpolarized xenon-129 (HPX), which was recently approved by the FDA. The project aims to develop an MRI-compatible, piston-based...
- This Project Grant award from the National Heart Lung and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) aims to develop a modern Electrical Impedance Tomography (EIT) device for monitoring children in the Intensive Care Unit (ICU). The $299,900 award to Goodlife Inventors LLC will fund efforts to (1) generate initial designs for an advanced lightweight EIT belt and (2) assess the technical feasibility of a miniaturized, easier to use EIT core device. If...
- This Project Grant award, provided by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837), funds the development of Heartpoint Global's IntelliSent - a minimally invasive, adjustable pulmonary flow restrictor system for pediatric and congenital heart disease patients. The $1,771,084 award supports efforts to (1) downsize the IntelliSent device to be suitable for patients from birth, including preclinical testing, (2) complete...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $499,932 to Safebvm Corp., a small disadvantaged business located in Boston, MA, to integrate the company's SOTAIR device with capnography monitoring to standardize manual ventilation techniques and improve patient outcomes. The SOTAIR device is designed to prevent complications associated with improper manual ventilation, which can lead to costly complications...
- This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), will evaluate the use of mobile devices to extract vital signs to monitor patients with asthma. The $459,127 award to M5 Enterprise, LLC (doing business as Emedical Sentry) aims to improve the detection and management of asthma attacks through remote patient monitoring. The goal is to enhance telehealth by incorporating video-based vital sign...
This federal Project Grant award from the National Heart Lung and Blood Institute under CFDA Program 93.837 - Cardiovascular Diseases Research provides $306,872 to Airalux Medical, Inc. to develop a digital incentive spirometry device. The goal is to improve patient adherence and clinical workflows for preventing post-surgical lung complications, which occur in 1 in 20 patients undergoing an overnight hospital stay. The device uses sensors and software to automatically track patient usage and display metrics on a mobile dashboard for clinician monitoring, addressing the current limitations of manual, self-reported incentive spirometry. This award aims to make incentive spirometry more effective in clinical settings by increasing patient engagement and clinician visibility into usage data. The project period runs from September 2025 to September 2026.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $306.9k | 9/4/25 |