SCH: a novel bias-mitigated multimodal oxygen monitor - annually, ~300,000 neonates are admitted to the neonatal intensive care unit (nicu) in the U.S., mostly due to respiratory distress
Active Project Grant Awarded Last action
- Award ID
- R01HL172293
- Recipient
-
Worcester Polytechnic Institute UEI HJNQME41NBU4
- Awarding agency
-
National Heart Lung and Blood Institute
National Institutes of Health, Department of Health and Human Services
- Obligated
- $419,177
Award facts
- Assistance listing
- 93.310 Trans-NIH Research Support
- Completion date 80% complete
- Funding agency
- Office of the Director National Institutes of Health, Department of Health and Human Services
- Place of performance
- Worcester, MA 01609, USA
Award details come from USAspending.gov.
Description
After a successful medical treatment in the nicu, earlier discharge to a stable home life could improve the chance of survival for neonates. However, the outpatient management of babies with fragile respiratory status is challenging in the absence of reliable remote monitoring devices suitable for use at home. Due to the small form factor and ease of use, contemporary home monitoring devices deploy sensors measuring SPO2, the saturation of hemoglobin bound to oxygen. Nevertheless, accurate assessment of oxygenation is complicated and not possible with only one parameter. Therefore, in clinical practice, invasive blood gas measurements - including partial pressure of oxygen (PAO2), which is the free dissolved oxygen (not bound to hemoglobin) - are not entirely replaced with SPO2. PAO2 is an essential cardio-respiratory measurement and the direct indication of lung effectiveness. A direct noninvasive method of assessing PAO2 is PTCO2, oxygen gas that diffuses through the skin. Creating an ability to sense two respiratory parameters (PTCO2 and SPO2) with one wearable is unique and superior to the current practice of measuring only SPO2, filling an important GAP in miniaturization of the transcutaneous blood gas monitors.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $20,000 | |
| Amendment | -$20,000 | |
| Amendment | $284,115 | |
| Original award | $135,062 |
Subawards
| Subrecipient | Amount | Awarded |
|---|---|---|
| Michigan State University | $391,445 | |
| University Of Massachusetts Medical School | $196,315 |
Quick answers
Who received award R01HL172293?
R01HL172293 was awarded to Worcester Polytechnic Institute by National Heart Lung and Blood Institute (National Institutes of Health) on September 1, 2023.
How much is award R01HL172293 worth?
$419,177 has been obligated on R01HL172293.
Which agency awarded R01HL172293?
National Heart Lung and Blood Institute (National Institutes of Health) awarded R01HL172293, with funding from Office of the Director (National Institutes of Health).
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