This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $806,550 to The University of Texas Southwestern Medical Center to conduct a multi-center study exploring optimal blood pressure management approaches to reduce cardiovascular complications in liver transplant recipients. The study aims to determine the net clinical benefit of blood pressure lowering, investigate the utility of cardiac biomarkers for risk stratification, and identify optimal hypertension treatment strategies that maximize cardiovascular benefit while minimizing harms to the liver, kidney, and brain. The study will leverage the existing infrastructure of the ACCT NOW Consortium, comprised of 6 U.S. transplant centers, and involve prospective data collection from 1,268 liver transplant recipients over a 2-year period with outcomes tracked up to 5 years post-transplant. Sub-awards to the University of California, San Francisco, Columbia University, and the University of Pennsylvania will support study site activities such as participant recruitment, data collection, and biospecimen storage and analysis.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $806.6k | 8/8/24 |
Grant Number | Description | Subgrantee | Prime Award | Dollars Obligated (Click to sort descending) | Updated At (Click to sort ascending) |
|---|---|---|---|---|---|
GMO250101PO3645S | The Regents Of The University Of California. San Francisco | Project Grant R01HL171207 | $83.9k | 1/27/25 | |
GMO251106PO3571S | The Trustees Of Columbia University In The City Of New York | Project Grant R01HL171207 | $79.2k | 12/15/24 | |
GMO251016PO3554S | The Trustees Of The University Of Pennsylvania | Project Grant R01HL171207 | $78.9k | 11/5/24 |